Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

49 trials with published results (10%)

Research Maturity

195 completed trials (41% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

5.7%

27 terminated out of 474 trials

Success Rate

87.8%

+1.3% vs benchmark

Late-Stage Pipeline

8%

40 trials in Phase 3/4

Results Transparency

25%

49 of 195 completed with results

Key Signals

49 with results88% success27 terminated

Data Visualizations

Phase Distribution

263Total
Not Applicable (206)
P 1 (3)
P 2 (14)
P 3 (16)
P 4 (24)

Trial Status

Completed195
Unknown95
Recruiting77
Active Not Recruiting44
Terminated27
Not Yet Recruiting17

Trial Success Rate

87.8%

Benchmark: 86.5%

Based on 195 completed trials

Clinical Trials (474)

Showing 20 of 20 trials
NCT07734025Not ApplicableNot Yet RecruitingPrimary

A Prospective, Multi-centre, Single Arm, Pivotal Clinical Study to Determine the Safety and Effectiveness of Crea Aortic Valve for Use as a Replacement Aortic Heart Valve

NCT05283356Phase 4Recruiting

Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation

NCT05172973Not ApplicableRecruiting

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

NCT06773780Not ApplicableRecruitingPrimary

Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management

NCT04372381Not ApplicableWithdrawnPrimary

Supra-Annular vs. Annular ValvEs for Small Annuli

NCT07715279Phase 2Not Yet Recruiting

Vericiguat for the Inhibition of Calcific Aortic Valve Stenosis Progression

NCT07709858RecruitingPrimary

CHATEAU Registry: Clinical Outcomes After Transcatheter Aortic Valve Replacement

NCT07566624Recruiting

Spanish Prospective Registry of Hydra THV for Transcatheter Aortic Valve Implantation

NCT07477002Not ApplicableActive Not RecruitingPrimary

Post-Dilatation in Balloon-Expandable TAVI Prostheses

NCT05672836Phase 4RecruitingPrimary

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement

NCT07276711Not ApplicableRecruitingPrimary

CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material

NCT06557798RecruitingPrimary

REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure

NCT02817789Phase 3TerminatedPrimary

Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI)

NCT06049654Not ApplicableRecruitingPrimary

Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication

NCT02729519Not ApplicableCompletedPrimary

TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3

NCT05308888Phase 2RecruitingPrimary

Impact of Local Tissue Inflammation on Intramyocardial Conduction Pathways Post Percutaneous Valve : Evaluation by Positron Emission Tomography on Exploratory Cohort

NCT07626710RecruitingPrimary

Impact of Trans-catheter Aortic Valve Implantation on Renal Function

NCT07626567Not Yet RecruitingPrimary

Prospective Neuropsychological Evaluation of the Implementation of a Heart Valve Unit (HVU-NEURO)

NCT04722250Not ApplicableActive Not Recruiting

SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial

NCT07284550RecruitingPrimary

Smartphone Based Digital Screening for Aortic Valve Stenosis

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