Visual Remapping to Aid Reading With Field Loss
Remapping the Visual Field to Aid Reading With Central Scotomas
1 other identifier
interventional
108
1 country
1
Brief Summary
Reading performance in patients with Central Vision Loss and age matched controls with artificial scotomas will be measured with and without different kinds of remapping of missing text to different parts of the visual field.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Feb 2022
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 28, 2019
CompletedFirst Posted
Study publicly available on registry
February 21, 2019
CompletedStudy Start
First participant enrolled
February 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 1, 2026
April 22, 2026
April 1, 2026
4.4 years
January 28, 2019
April 16, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
Reading Speed for Individual Words
How quickly participants can correctly read displayed text
Measured during third visit- each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Reading Speed for Sentences
How quickly participants can correctly read displayed text
Measured during fourth visit- each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Reading Speed for Natural Text Samples
How quickly participants can correctly read displayed text
Measured during fifth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Reading error rate for Individual Words
How many mistakes participants make
Measured during third visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Reading error rate for Sentences
How many mistakes participants make
Measured during fourth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Reading error rate for Natural Text Samples
How many mistakes participants make
Measured during fifth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Secondary Outcomes (5)
Eye fixation quality for words
Measured during third visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Eye fixation quality for sentences
Measured during fourth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Eye movement quality for sentences
Measured during fourth visit
Eye fixation quality for natural text samples
Measured during fifth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Eye movement quality for natural text samples
Measured during fifth visit; each visit is one day only and this measure refers to data gathered during a < 1 hr long reading session during that day
Study Arms (2)
Patients with scotoma
EXPERIMENTALNo remapping (control condition), traditional remapping, personalized remapping
Normally sighted with artificial scotoma
ACTIVE COMPARATORNo remapping (control condition), traditional remapping, personalized remapping
Interventions
Shifting text outside of scotoma
Shifting text based on individual letter-based perimetry
Eligibility Criteria
You may qualify if:
- years or older
- Central vision loss of at least 5 deg diameter, including the fovea, from bilateral central scotomas
- Stable fixation (+/- 1 deg) using their PRL.
- No cognitive impairment as indicated by a Mini-Mental State Examination (MMSE).
- Satisfactory calibration achievable using eye tracker
You may not qualify if:
- Central vision loss of less than 5 deg diameter; scotomas that do not cover the fovea; unilateral scotomas
- Poor fixation (worse than+/- 1 deg) using their PRL.
- Cognitive impairment as indicated by a Mini-Mental State Examination (MMSE).
- Satisfactory calibration not achievable using eye tracker
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Minnesota
Minneapolis, Minnesota, 55455, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Stephen Engel, Ph.D.
University of Minnesota
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 28, 2019
First Posted
February 21, 2019
Study Start
February 1, 2022
Primary Completion (Estimated)
July 1, 2026
Study Completion (Estimated)
July 1, 2026
Last Updated
April 22, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, ANALYTIC CODE
- Time Frame
- Once results are published.
- Access Criteria
- Research group.
Perimetry, psychophysical and eye-tracking data will be deidentified upon acquisition, and indexed using only a subject code. These data will be stored on a secure server for sharing upon request by a PI of a research team. We will offer psychophysical and eye tracking data along with appropriate metadata specifying details of the test (remapping used, stimulus protocol, etc) and data format.