Key Insights

Highlights

Success Rate

85% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

8.0%

2 terminated out of 25 trials

Success Rate

84.6%

-1.9% vs benchmark

Late-Stage Pipeline

16%

4 trials in Phase 3/4

Results Transparency

45%

5 of 11 completed with results

Key Signals

5 with results85% success

Data Visualizations

Phase Distribution

23Total
Not Applicable (1)
P 1 (8)
P 2 (10)
P 3 (4)

Trial Status

Completed11
Recruiting6
Active Not Recruiting4
Terminated2
Unknown2

Trial Success Rate

84.6%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (25)

Showing 20 of 20 trials
NCT02143466Phase 1Active Not RecruitingPrimary

AZD9291 in Combination With Ascending Doses of Novel Therapeutics

NCT01802632Phase 1CompletedPrimary

AZD9291 First Time In Patients Ascending Dose Study

NCT05777603Phase 1RecruitingPrimary

Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-small Cell Lung Cancer

NCT06908993Phase 3RecruitingPrimary

Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated

NCT04940325Phase 2Active Not Recruiting

Datopotamab Deruxtecan (Dato-DXd, DS-1062a) in Advanced and/or Unresectable Non-Small Cell Lung Cancer

NCT02157883Phase 1CompletedPrimary

Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)

NCT05318573Phase 2Active Not Recruiting

A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer

NCT04032847Phase 1TerminatedPrimary

ATL001 in Patients With Advanced Unresectable or Metastatic NSCLC

NCT04886401RecruitingPrimary

Retrospective Observational Study on Prediction of Response to PD-1 Immunotherapy in Patients with NSCLC

NCT04685135Phase 3Active Not Recruiting

Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation

NCT06107374Phase 2RecruitingPrimary

Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18F]-FARAG

NCT06406166Not ApplicableRecruitingPrimary

Lifei Xiaoji Wan in Treatment of Advanced NSCLC

NCT04144608Phase 2CompletedPrimary

Toripalimab Combined With Double Platinum-based Chemotherapy for Initially Unresectable NSCLC

NCT05004974Phase 2RecruitingPrimary

Sintilimab With Pemigatinib in Patients With PD-L1-positive and FGFR Mutated Advanced Non-small Cell Lung Cancer

NCT02163733Phase 1CompletedPrimary

Study to Determine the Effect of Food on the Blood Levels of AZD9291 Following Oral Dosing of a Tablet Formulation in Patients With Non-Small Cell Lung Cancer

NCT04785365Phase 2Terminated

Long-Term Follow-Up Study of Patients Receiving ATL001

NCT02407327CompletedPrimary

Individualized Treatment of Patients With Advanced NSCLC: Potential Application for Circulating Tumor Cells (CTC) Molecular and Phenotypical Profiling

NCT03452150Phase 1CompletedPrimary

D-0316 First Time in Patients Ascending Dose Study

NCT03351361Phase 3CompletedPrimary

Nivolumab and Ipilimumab Versus Chimiotherapy in First Line Treatment in PS 2 or Elderly in Advanced NSCLC Patients

NCT04755738Phase 2UnknownPrimary

Almonertinib Plus Microwave Ablation in Advanced Non-small Cell Lung Cancer

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