Key Insights

Highlights

Success Rate

74% trial completion

Published Results

23 trials with published results (23%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

10.2%

10 terminated out of 98 trials

Success Rate

74.4%

-12.2% vs benchmark

Late-Stage Pipeline

7%

7 trials in Phase 3/4

Results Transparency

79%

23 of 29 completed with results

Key Signals

23 with results74% success

Data Visualizations

Phase Distribution

87Total
Not Applicable (1)
Early P 1 (2)
P 1 (43)
P 2 (34)
P 3 (4)
P 4 (3)

Trial Status

Completed29
Recruiting23
Unknown17
Active Not Recruiting11
Terminated10
Not Yet Recruiting5

Trial Success Rate

74.4%

Benchmark: 86.5%

Based on 29 completed trials

Clinical Trials (98)

Showing 20 of 20 trials
NCT07574047Phase 2Not Yet Recruiting

MELCHRONO: A Prospective Randomized Study Investigating Chrono-immunotherapy for Advanced Melanoma.

NCT01134614Phase 2Active Not RecruitingPrimary

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

NCT07634380Phase 1Recruiting

Sitagliptin With Pembro in RCC and Melanoma

NCT05629546Phase 1RecruitingPrimary

Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors

NCT04462406Phase 2Active Not RecruitingPrimary

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

NCT06264180Phase 3RecruitingPrimary

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

NCT02650986Phase 1Active Not Recruiting

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

NCT05967533Phase 1Suspended

The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors

NCT03311308Phase 1Active Not RecruitingPrimary

A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

NCT06298734Not ApplicableRecruiting

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT07027488Phase 1Recruiting

AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

NCT04695977Phase 2Terminated

CMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced Melanoma

NCT07405086Phase 4Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT04495257Phase 1CompletedPrimary

A Study of APX005M in Combination With Nivolumab and Ipilimumab in Treatment Naïve Patients With Advanced Melanoma or Renal Cell Carcinoma (RCC)

NCT05039801Phase 1Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

NCT04514484Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

NCT02965716Phase 2Active Not RecruitingPrimary

Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma

NCT07099430Phase 1RecruitingPrimary

A Trial of LBL-024 Monotherapy, LBL-024 Combined With LBL-007 or Toripalimab in Patients With Advanced Melanoma

NCT06889766Phase 1RecruitingPrimary

NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma

NCT06594991Phase 2RecruitingPrimary

A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

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