Key Insights

Highlights

Success Rate

74% trial completion

Published Results

23 trials with published results (23%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

10.2%

10 terminated out of 98 trials

Success Rate

74.4%

-12.1% vs benchmark

Late-Stage Pipeline

8%

8 trials in Phase 3/4

Results Transparency

79%

23 of 29 completed with results

Key Signals

23 with results74% success

Data Visualizations

Phase Distribution

87Total
Not Applicable (1)
Early P 1 (2)
P 1 (43)
P 2 (33)
P 3 (4)
P 4 (4)

Trial Status

Completed29
Recruiting24
Unknown17
Active Not Recruiting10
Terminated10
Not Yet Recruiting6

Trial Success Rate

74.4%

Benchmark: 86.5%

Based on 29 completed trials

Clinical Trials (98)

Showing 20 of 20 trials
NCT07405086Phase 4Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT04495257Phase 1CompletedPrimary

A Study of APX005M in Combination With Nivolumab and Ipilimumab in Treatment Naïve Patients With Advanced Melanoma or Renal Cell Carcinoma (RCC)

NCT07634380Phase 1Not Yet Recruiting

Sitagliptin With Pembro in RCC and Melanoma

NCT05039801Phase 1Recruiting

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

NCT01134614Phase 2Active Not RecruitingPrimary

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

NCT04514484Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

NCT02965716Phase 2Active Not RecruitingPrimary

Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma

NCT07099430Phase 1RecruitingPrimary

A Trial of LBL-024 Monotherapy, LBL-024 Combined With LBL-007 or Toripalimab in Patients With Advanced Melanoma

NCT06889766Phase 1RecruitingPrimary

NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma

NCT06264180Phase 3RecruitingPrimary

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

NCT04462406Phase 2Active Not RecruitingPrimary

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

NCT06594991Phase 2RecruitingPrimary

A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

NCT04640545Phase 1CompletedPrimary

A Study to Assess LBL-007 in Combination With Toripalimab and Axitinib Tablets Subjects With Advanced Melanoma

NCT07310784Phase 2RecruitingPrimary

A Phase II Trial of LM103 in Advanced Melanoma

NCT06697301Phase 2RecruitingPrimary

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

NCT07562841Phase 1RecruitingPrimary

Au-TMP and Radiotherapy for Advanced Melanoma With Anti-PD-1 Therapy

NCT07574047Phase 4Not Yet Recruiting

MELCHRONO: A Prospective Randomized Study Investigating Chrono-immunotherapy for Advanced Melanoma.

NCT04902040Phase 1Terminated

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

NCT07504796Phase 4Recruiting

ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab

NCT05969860Phase 2Recruiting

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

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