Key Insights

Highlights

Success Rate

74% trial completion

Published Results

24 trials with published results (24%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

9.9%

10 terminated out of 101 trials

Success Rate

74.4%

-12.2% vs benchmark

Late-Stage Pipeline

7%

7 trials in Phase 3/4

Results Transparency

83%

24 of 29 completed with results

Key Signals

24 with results74% success

Data Visualizations

Phase Distribution

90Total
Not Applicable (2)
Early P 1 (2)
P 1 (43)
P 2 (36)
P 3 (5)
P 4 (2)

Trial Status

Completed29
Recruiting22
Unknown17
Active Not Recruiting11
Terminated10
Not Yet Recruiting8

Trial Success Rate

74.4%

Benchmark: 86.6%

Based on 29 completed trials

Clinical Trials (101)

Showing 20 of 20 trials
NCT01134614Phase 2Active Not RecruitingPrimary

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

NCT07836712Phase 2Not Yet Recruiting

Multiple Adjunct Therapies to Improve Immunotherapy Treatment in Patients With Locally Advanced or Metastatic Melanoma or Advanced Hepatocellular Cancer

NCT05629546Phase 1SuspendedPrimary

Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors

NCT07562841Phase 1RecruitingPrimary

Au-TMP and Radiotherapy for Advanced Melanoma With Anti-PD-1 Therapy

NCT07819474Not ApplicableNot Yet Recruiting

Optimizing Tumor-Infiltrating Lymphocyte (TIL) Harvest Site and Patient Selection With CD8-PET Imaging in Patients With

NCT04462406Phase 2Active Not RecruitingPrimary

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

NCT07815574Phase 3Not Yet Recruiting

iSCIB1+ in Combination With Ipilimumab and Nivolumab as First-Line Treatment for Advanced Unresectable Melanoma

NCT04796194Phase 2CompletedPrimary

Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma

NCT07310784Phase 2RecruitingPrimary

A Phase II Trial of LM103 in Advanced Melanoma

NCT07504796Phase 2Recruiting

ctDNA-guided Addition of Ipilimumab to Patients Receiving Nivolumab and Relatlimab

NCT06298734Not ApplicableRecruiting

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT06214156Phase 1RecruitingPrimary

A Clinical Study of T3011 in Subjects With Advanced Melanoma

NCT07574047Phase 2Not Yet Recruiting

MELCHRONO: A Prospective Randomized Study Investigating Chrono-immunotherapy for Advanced Melanoma.

NCT07634380Phase 1Recruiting

Sitagliptin With Pembro in RCC and Melanoma

NCT06264180Phase 3RecruitingPrimary

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

NCT02650986Phase 1Active Not Recruiting

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

NCT05967533Phase 1Suspended

The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors

NCT03311308Phase 1Active Not RecruitingPrimary

A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

NCT07027488Phase 1Recruiting

AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

NCT04695977Phase 2Terminated

CMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced Melanoma

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