Key Insights

Highlights

No notable highlights available yet

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

14.3%

4 terminated out of 28 trials

Success Rate

20.0%

-66.5% vs benchmark

Late-Stage Pipeline

7%

2 trials in Phase 3/4

Results Transparency

300%

3 of 1 completed with results

Key Signals

3 with results

Data Visualizations

Phase Distribution

26Total
Not Applicable (3)
Early P 1 (1)
P 1 (10)
P 2 (10)
P 3 (1)
P 4 (1)

Trial Status

Recruiting11
Active Not Recruiting7
Terminated4
Not Yet Recruiting2
Withdrawn2
Unknown1

Trial Success Rate

20.0%

Benchmark: 86.5%

Based on 1 completed trials

Clinical Trials (28)

Showing 20 of 20 trials
NCT07017829Phase 2RecruitingPrimary

GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer

NCT07405086Phase 4Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT03191149Phase 2RecruitingPrimary

Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change

NCT04902040Phase 1Terminated

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

NCT06096844Phase 3RecruitingPrimary

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

NCT07543172Phase 2Not Yet RecruitingPrimary

CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer

NCT03831932Phase 1Active Not RecruitingPrimary

Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer

NCT04491942Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

NCT04762199Phase 1RecruitingPrimary

MRX-2843 and Osimertinib for the Treatment of Advanced EGFR Mutant Non-small Cell Lung Cancer

NCT04514484Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

NCT07322341Phase 2Not Yet RecruitingPrimary

SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer

NCT05166616Phase 1Active Not RecruitingPrimary

Minnelide and Osimertinib for the Treatment of Advanced EGFR Mutated Non-Small Cell Lung Cancer

NCT06731270Phase 2RecruitingPrimary

Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy

NCT06073431Recruiting

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

NCT05339022Not ApplicableCompletedPrimary

Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial

NCT04396535Phase 2TerminatedPrimary

Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer

NCT05334329Phase 1Active Not RecruitingPrimary

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

NCT06249282Phase 1RecruitingPrimary

Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer

NCT05096663Phase 2Active Not RecruitingPrimary

Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

NCT02983578Phase 2Active Not Recruiting

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Scroll to load more

Research Network

Activity Timeline