Key Insights

Highlights

Success Rate

80% trial completion

Published Results

16 trials with published results (9%)

Research Maturity

74 completed trials (43% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

11.1%

19 terminated out of 171 trials

Success Rate

79.6%

-7.0% vs benchmark

Late-Stage Pipeline

26%

45 trials in Phase 3/4

Results Transparency

22%

16 of 74 completed with results

Key Signals

16 with results80% success19 terminated

Data Visualizations

Phase Distribution

110Total
Not Applicable (39)
P 1 (3)
P 2 (23)
P 3 (19)
P 4 (26)

Trial Status

Completed74
Unknown36
Recruiting27
Terminated19
Withdrawn6
Not Yet Recruiting5

Trial Success Rate

79.6%

Benchmark: 86.5%

Based on 74 completed trials

Clinical Trials (171)

Showing 20 of 20 trials
NCT04481919Phase 2Active Not Recruiting

Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)

NCT00561483CompletedPrimary

Sequential Cystatin C Levels and Renal Impairment in Acute Heart Failure

NCT04886128CompletedPrimary

Improving Diagnostic Accuracy for Acute Heart Failure

NCT07577596Phase 4RecruitingPrimary

Infusion of Furosemide to Improve Diuretic Efficiency in Acute Heart Failure

NCT06008197Phase 3Recruiting

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

NCT04363697Phase 4CompletedPrimary

Dapagliflozin and Effect on Cardiovascular Events in Acute Heart Failure -Thrombolysis in Myocardial Infarction 68 (DAPA ACT HF-TIMI 68)

NCT07434466Not ApplicableNot Yet RecruitingPrimary

Ketone Ester for Treatment Of Acute Heart Failure

NCT05613218Phase 2CompletedPrimary

Oxygen Targets in Acute Heart Failure With Pulmonary Congestion

NCT03999138RecruitingPrimary

MRI Assessment of Pulmonary Edema in Acute Heart Failure

NCT05276219Phase 4Recruiting

Optimized Treatment of Pulmonary Edema or Congestion

NCT07508891RecruitingPrimary

Characterisation of phenotYpes in aCute Heart faiLure patiEnts

NCT06465498Not ApplicableRecruitingPrimary

Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography

NCT07295522Phase 4Not Yet Recruiting

Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap?

NCT05305495Phase 4CompletedPrimary

Empagliflozin in Acute Heart Failure

NCT07447037Not ApplicableNot Yet RecruitingPrimary

Integrating Aerobic, Respiratory, and Cognitive Training in Acute Heart Failure

NCT05392764Phase 3RecruitingPrimary

Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure

NCT07397650Phase 4RecruitingPrimary

Efficacy and Safety With Early Treatment of Finerenone in Hospitalized Patients With Heart Failure

NCT05518396Active Not RecruitingPrimary

Prospective Validation of the CoDE-HF Algorithm for the Diagnosis of Acute Heart Failure

NCT03892148Phase 4Completed

Protocol of Diuretics Use in Congestive Therapy in Heart Failure

NCT05668676Phase 2CompletedPrimary

Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF )

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