Key Insights

Highlights

Success Rate

79% trial completion

Published Results

15 trials with published results (9%)

Research Maturity

72 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

11.2%

19 terminated out of 170 trials

Success Rate

79.1%

-7.4% vs benchmark

Late-Stage Pipeline

26%

44 trials in Phase 3/4

Results Transparency

21%

15 of 72 completed with results

Key Signals

15 with results79% success19 terminated

Data Visualizations

Phase Distribution

109Total
Not Applicable (39)
P 1 (3)
P 2 (23)
P 3 (19)
P 4 (25)

Trial Status

Completed72
Unknown36
Recruiting27
Terminated19
Withdrawn6
Not Yet Recruiting5

Trial Success Rate

79.1%

Benchmark: 86.5%

Based on 72 completed trials

Clinical Trials (170)

Showing 20 of 20 trials
NCT06008197Phase 3Recruiting

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

NCT07434466Not ApplicableNot Yet RecruitingPrimary

Ketone Ester for Treatment Of Acute Heart Failure

NCT05276219Phase 4Recruiting

Optimized Treatment of Pulmonary Edema or Congestion

NCT07508891RecruitingPrimary

Characterisation of phenotYpes in aCute Heart faiLure patiEnts

NCT06465498Not ApplicableRecruitingPrimary

Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography

NCT07295522Phase 4Not Yet Recruiting

Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap?

NCT05305495Phase 4CompletedPrimary

Empagliflozin in Acute Heart Failure

NCT07447037Not ApplicableNot Yet RecruitingPrimary

Integrating Aerobic, Respiratory, and Cognitive Training in Acute Heart Failure

NCT05392764Phase 3RecruitingPrimary

Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure

NCT07397650Phase 4RecruitingPrimary

Efficacy and Safety With Early Treatment of Finerenone in Hospitalized Patients With Heart Failure

NCT05518396Active Not RecruitingPrimary

Prospective Validation of the CoDE-HF Algorithm for the Diagnosis of Acute Heart Failure

NCT03892148Phase 4Completed

Protocol of Diuretics Use in Congestive Therapy in Heart Failure

NCT05668676Phase 2CompletedPrimary

Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF )

NCT04481919Phase 2Active Not Recruiting

Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)

NCT05613218Phase 2RecruitingPrimary

Oxygen Targets in Acute Heart Failure With Pulmonary Congestion

NCT00561483CompletedPrimary

Sequential Cystatin C Levels and Renal Impairment in Acute Heart Failure

NCT03836079Not ApplicableCompleted

SVC Occlusion in Subjects With Acute Decompensated Heart Failure

NCT05916586Not ApplicableCompletedPrimary

Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure

NCT06587854RecruitingPrimary

a PRagmatic Observational Study of Congestion proFILes in patiEnts With Acute Heart Failure

NCT06006754Completed

Influence of Enteral Microbiome on Mortality of Patients With Cardiogenic Shock

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Research Network

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