The RHINOME study

You may not qualify if:

• Outpatient recruitment pool: 1. Known hypersensitivity to the active substance or any excipient in tezepelumab.
• Outpatient recruitment pool: 2. Participation in an interventional clinical trial within 3 months of the baseline visit, or receipt of any investigational medicinal product within 3 months or 5 half-lives, whichever is longer.
• Outpatient recruitment pool: 3. Participation in other studies that, in the investigator's view, will impact the study outcomes.
• Outpatient recruitment pool: 4. Other clinically significant medical disease or uncontrolled concomitant disease likely, in the investigator's opinion, to require a change in therapy or to impair the ability to participate.
• Outpatient recruitment pool: 5. Unwilling or unable, in the investigator's opinion, to participate in study procedures and assessments.
• TR-ABC recruitment pool: 1. Known quality issues with airway samples making them insufficient for planned key analyses.
• TR-ABC recruitment pool: 2. Any participant who has specifically withdrawn their consent for future use of samples in the 3TR-ABC study.