NCT07901283

Completed

Comparative Analysis of Intralesional Platelet-Rich Plasma, ...

Aya Ashraf Fouda Source

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Other study identifiers

Sponsor study identifier

36264MS671/8/25

Study Type

interventional

Actual enrollment (reported)

30

Locations

1 country

Sites

1

Timeline

Study Start

March 10, 2025

Actual (reported)

Primary Completion

March 15, 2026

Actual (reported)

Study Completion

May 1, 2026

Actual (reported)

Brief Summary

The aim of this clinical trial is to evaluate the efficacy and safety of platelet-rich plasma, insulin and vitamin C in the management of linear atrophic scars. The participants were allocated randomly into one of the three groups. The patients will be evaluated at the end of the follow-up period together with assessment of skin thickness using ultrasound before treatment and at the end of follow-up. Each patient received four treatment sessions at two-week interval

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 30 participants
Study completion date: May 1, 2026
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
March 10, 2025
Actual (reported)
Primary Completion
March 15, 2026
Actual (reported)
Study Completion
May 1, 2026
Actual (reported)
First Submitted
October 22, 2026
Actual (reported)
First Posted
October 28, 2026
Actual (reported)

Last Updated: October 28, 2026
Status Verified: October 2026
Last Update Submitted: October 27, 2026

Conditions

Linear Atrophic Scars

Outcome Measures

Primary Outcomes (1)

Clinical improvement
Using quartile grading scale
2 months after last session

Secondary Outcomes (1)

Ultrasound evaluation of skin thickness at the site of scar
Baseline and 2 months after last session

Study Arms (3)

Platelet rich plasma injection

ACTIVE COMPARATOR

Injection of plateler rich plasma

Other: Intradermal injection of autologous platelet rich plasma

Injection of NPH insulin

ACTIVE COMPARATOR

Drug: Intradermal injection of NPH insulin

Injection of Vitamin C

ACTIVE COMPARATOR

Drug: Intradermal injection of Vitamin C

Interventions

Intradermal injection of autologous platelet rich plasmaOther

4 sessions at two weeks interval

Platelet rich plasma injection

Intradermal injection of NPH insulinDrug

4 sessions at two weeks interval

Injection of NPH insulin

Eligibility Criteria

Age18 Years - 50 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64)

You may qualify if:

patients with linear atrophic scars who didn't receive treatments for their scars 6 months before enrollment in the study

You may not qualify if:

Sponsors & Collaborators

Aya Ashraf Fouda
Otherlead

Study Sites (1)

Faculty of Medicine

Tanta, Gharbia Governorate, Egypt

Enrollment

30 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Lecturer of Dermatology and Venereology Tanta University

Study Record Dates

First Submitted

October 22, 2026

First Posted

October 28, 2026

Study Start

March 10, 2025

Actual (reported)

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Intradermal injection of Vitamin CDrug

Four sessions at two weeks interval

Injection of Vitamin C

pregnant and lactating women Patients with history of keloid scars- bleeding and coagulation disorders- autoimmune diseases

Contact the study team to confirm eligibility.

Primary Completion

March 15, 2026

Actual (reported)

Study Completion

May 1, 2026

Actual (reported)

Last Updated

October 28, 2026

Record last verified: 2026-10

Data Sharing

IPD Sharing: Will not share

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT07901283
Data provider: ClinicalTrials.gov
Source updated: 2026-10-28
Normalization version: ctgov-2

Open registry record

Source retrieved: 2026-10-30 23:02:53 UTC

Locations

EG(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (3)

Platelet rich plasma injection

Injection of NPH insulin

Injection of Vitamin C

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Enrollment

Study Design

Study Record Dates

Data Sharing

Source record

Locations