Trials Sponsors Conditions Drugs Pricing

Conditions

Migraine Photophobia Cognitive Function Assessment Headache Light Sensitivity Light

Keywords

migrainephotophobiaLight Sensitivityheadachecognitive functionlighting

Outcome Measures

Primary Outcomes (1)

Visual Discomfort
Participants reported their visual discomfort using an 11-point numeric rating scale ranging from 0 (no discomfort) to 10 (extreme discomfort). The primary visual discomfort outcome was the mean of the seven ratings collected at minutes 2-8.
Each minute from minutes 2 through 8 of each light exposure

Secondary Outcomes (3)

Digit Symbol Substitution Test
Minute 8 after onset of light exposure
Headache Intensity
Minute 8 after onset of light exposure

Study Arms (2)

Optimized White Light

EXPERIMENTAL

Spectrally Optimized White Light

Other: Optimized Ambient White Light

Conventional White Light

ACTIVE COMPARATOR

Other: Conventional White Light

Interventions

Optimized Ambient White LightOther

Green-enriched, spectrally optimized white light (λpeak = 525 nm)

Optimized White Light

Conventional White LightOther

conventional white light (λpeak = 450 nm)

Conventional White Light

Eligibility Criteria

Age18 Years - 45 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Ages 18-45 years
Able to communicate in English

You may not qualify if:

Sponsors & Collaborators

Flinn Foundation
Type not reportedcollaborator
Arizona State University
Otherlead

Study Sites (1)

Arizona State University

Tempe, Arizona, 85281, United States

MeSH Terms

Conditions

Migraine DisordersPhotophobiaHeadache

Condition Hierarchy (Ancestors)

Headache Disorders, PrimaryHeadache DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVision DisordersSensation DisordersNeurologic ManifestationsEye DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsPain

Enrollment

40 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: SINGLE
Who Masked: PARTICIPANT
Purpose: TREATMENT
Intervention Model: CROSSOVER
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Associate Professor

Study Record Dates

First Submitted

October 19, 2026

First Posted

October 27, 2026

Study Start

June 27, 2025

Actual (reported)

Impact of Optimized White Light on Visual Discomfort, Headache Intensity, and Cognitive Performance Among Those With Migraine

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (2)

Optimized White Light

Conventional White Light

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (2)

Optimized White Light

Conventional White Light

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

Source record

Locations