Trials Sponsors Conditions Drugs Pricing

Conditions

Coronary Artery Disease Left Ventricular Systolic Dysfunction Gastric Contents

Keywords

Gastric UltrasonographyCoronary Artery Bypass Grafting (CABG)Left Ventricular Ejection Fraction (LVEF)Perlas Grading SystemGastric Volume

Outcome Measures

Primary Outcomes (1)

Distribution of Perlas Gastric Ultrasound Grades Between LVEF Groups
The primary outcome is the comparison of Perlas gastric ultrasound grade distributions between patients with LVEF \<40% and LVEF ≥40%. Gastric contents will be assessed before anesthesia induction using the Perlas grading system: Grade 0, empty antrum in both supine and right lateral decubitus positions; Grade 1, clear fluid visible only in the right lateral decubitus position; and Grade 2, clear fluid visible in both positions. The number and percentage of patients in each grade will be compared between groups.
Preoperatively, immediately before induction of general anesthesia

Secondary Outcomes (4)

Association Between LVEF and Estimated Gastric Volume (mL/kg)
Preoperatively, immediately before induction of general anesthesia

Study Arms (2)

Group L-EF - Reduced LVEF (LVEF <40%)

This cohort will include 25 adult patients scheduled for elective coronary artery bypass grafting (CABG) surgery with a preoperative left ventricular ejection fraction (LVEF) \<40%, as determined by transthoracic echocardiography. Before induction of general anesthesia, patients will undergo gastric ultrasonography to assess Perlas grade, gastric antral cross-sectional area, estimated gastric volume, and the presence of high-risk gastric contents. No experimental therapeutic intervention will be administered.

Diagnostic Test: Gastric Ultrasonography

Group N-EF - (LVEF ≥40%)

This cohort will include 25 adult patients scheduled for elective coronary artery bypass grafting (CABG) surgery with a preoperative left ventricular ejection fraction (LVEF) ≥40%, as determined by transthoracic echocardiography. Before induction of general anesthesia, patients will undergo gastric ultrasonography to assess Perlas grade, gastric antral cross-sectional area, estimated gastric volume, and the presence of high-risk gastric contents. No experimental therapeutic intervention will be administered.

Diagnostic Test: Gastric Ultrasonography

Interventions

Gastric UltrasonographyDiagnostic test

Preoperative gastric ultrasonography will be performed before anesthesia induction by an experienced anesthesiologist blinded to LVEF values. Using a 2-5 MHz convex probe, the gastric antrum will be examined in supine and right lateral decubitus positions. Perlas grade, antral cross-sectional area, and gastric contents will be recorded. Gastric volume will be estimated only in patients with clear fluid. A high-risk stomach will be defined as gastric volume \>1.5 mL/kg or the presence of solid or thick particulate contents. The same protocol will be applied to both LVEF groups.

Group L-EF - Reduced LVEF (LVEF <40%)Group N-EF - (LVEF ≥40%)

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

The study population will consist of 50 adult patients (aged ≥18 years) who are scheduled for elective coronary artery bypass grafting (CABG) surgery with cardiopulmonary bypass at a single center. Eligible patients will be consecutively screened and enrolled after providing written informed consent. Participants will be categorized into two observational cohorts based on preoperative left ventricular ejection fraction (LVEF): LVEF \<40% (n=25) and LVEF ≥40% (n=25). No randomization or experimental treatment assignment will be performed.

You may qualify if:

Sponsors & Collaborators

Adiyaman University
Otherlead

Study Sites (1)

Adıyaman Training and Research Hospital

Adıyaman, 02040, Turkey (Türkiye)

FADİME TOSUN, MD, Associate ProfessorCONTACT+90 532 237 52 84 fadimetosun@gmail.com

MeSH Terms

Conditions

Coronary Artery DiseaseVentricular Dysfunction, Left

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular DiseasesVentricular Dysfunction

Central Study Contacts

FADİME TOSUN, MD, Associate Professor

CONTACT

+90 532 237 52 84 fadimetosun@gmail.com

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Assistant Professor

Study Record Dates

First Submitted

October 21, 2026

First Posted

October 27, 2026

Study Start

November 1, 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Primary Completion

March 1, 2027

Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass Surgery

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

Group L-EF - Reduced LVEF (LVEF <40%)

Group N-EF - (LVEF ≥40%)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (2)

Group L-EF - Reduced LVEF (LVEF <40%)

Group N-EF - (LVEF ≥40%)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations