Trials Sponsors Conditions Drugs Pricing

Conditions

Labor Pain

Keywords

RopivacaineLabor AnalgesiaDouble Dural Puncture Epidural

Outcome Measures

Primary Outcomes (1)

The ED₉₀ of ropivacaine
The ED₉₀ of ropivacaine required for parturients to achieve an numerical rating scale (NRS) pain score \<3 within 30 minutes following the initial administration.
When the fetus is delivered

Secondary Outcomes (4)

Visual analogue scale pain score
10, 20, and 30 minutes after initial administration
Bromage score
30, 60, 120, 180, and 240 minutes after initial administration
APGAR score
1 minute after delivery
APGAR score
5 minutes after delivery

Study Arms (1)

Double dural puncture epidural group

EXPERIMENTAL

Labor analgesia via double dural puncture epidural technique

Drug: 0.1% Ropivacaine

Interventions

0.1% RopivacaineDrug

An initial bolus of 0.1% ropivacaine , with a total volume of 10 mL (containing 10 mg ropivacaine), was administered to the first patient. For subsequent patients, the dose was adjusted in increments or decrements of 2 mL (2 mg 0.1% ropivacaine), based on whether a visual analogue scale pain score of less than 3 was achieved within 30 minutes after administration.

Double dural puncture epidural group

Eligibility Criteria

Age18 Years - 40 Years

Sexfemale

Healthy VolunteersNo

Age GroupsAdult (18-64)

You may qualify if:

Age 18-45 years
Singleton pregnancy at 37-42 weeks of gestation

Sponsors & Collaborators

General Hospital of Ningxia Medical University
Otherlead

MeSH Terms

Conditions

Labor Pain

Interventions

Ropivacaine

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

AnilidesAmidesOrganic ChemicalsAniline CompoundsAmines

Study Officials

Yi Chen
General Hospital of Ningxia Medical University
PRINCIPAL INVESTIGATOR

Central Study Contacts

Yi Chen

CONTACT

86-951-674-3252 czzyxgp@163.com

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

October 19, 2026

First Posted

October 26, 2026

Study Start

June 30, 2027

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Primary Completion

June 30, 2027

Estimated

The 90% Effective Initial Volume for Labor Analgesia Under Double Dural Puncture Epidural Technique

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (1)

Double dural puncture epidural group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (4)

Study Arms (1)

Double dural puncture epidural group

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record