NCT07887360

Brief Summary

This randomized controlled trial compares lower limb proprioceptive neuromuscular facilitation (PNF) combined with core stability training versus lower limb PNF alone in chronic stroke survivors. The study aims to determine whether adding core stability training produces greater improvements in dynamic balance and functional mobility.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P50-P75 for not_applicable stroke

Timeline
2mo left

Started Jul 2026

Shorter than P25 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress57%
Jul 2026Dec 2026

Study Start

First participant enrolled

July 25, 2026

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 14, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 21, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 25, 2026

Expected
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2026

Last Updated

October 21, 2026

Status Verified

October 1, 2026

Enrollment Period

5 months

First QC Date

October 14, 2026

Last Update Submit

October 14, 2026

Conditions

Stroke

Outcome Measures

Primary Outcomes (2)

  • Timed Up and Go (TUG) Test

    The Timed Up and Go (TUG) Test is a reliable clinical test used to assess functional mobility, dynamic balance, walking ability, and risk of falls. A reduction in completion time generally indicates improved functional mobility

    baseline and after 6 weeks of intervention.

  • 10-Meter Walk Test (10MWT)

    The 10-Meter Walk Test (10MWT) is a standardized clinical assessment used to measure walking speed (gait speed) in metres per second (m/s). Increased walking speed generally indicates improved walking performance.

    baseline and after 6 weeks of intervention.

Study Arms (2)

Lower Limb PNF Combined with Core Stability Training

EXPERIMENTAL

Lower limb PNF (D1/D2 diagonal and spiral patterns, rhythmic stabilization, functional PNF patterns) plus core stability exercises including bridging, planks, Swiss-ball activities and core integration; 5 times/week for 6 weeks; 30-35 minutes/session.

Other: Lower Limb PNF Combined with Core Stability Training

Lower Limb PNF alone

ACTIVE COMPARATOR

Lower limb PNF using D1/D2 diagonal and spiral patterns, rhythmic stabilization and functional PNF patterns without added core stability exercises; 5 times/week for 6 weeks; 30-35 minutes/session.

Other: Lower Limb PNF alone

Interventions

Lower Limb PNF aloneOTHER

Lower limb PNF using D1/D2 diagonal and spiral patterns, rhythmic stabilization and functional PNF patterns without added core stability exercises; 5 times/week for 6 weeks; 30-35 minutes/session.

Lower Limb PNF alone
Lower Limb PNF Combined with Core Stability TrainingOTHER

Lower limb PNF (D1/D2 diagonal and spiral patterns, rhythmic stabilization, functional PNF patterns) plus core stability exercises including bridging, planks, Swiss-ball activities and core integration; 5 times/week for 6 weeks; 30-35 minutes/session

Lower Limb PNF Combined with Core Stability Training

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 40 years Male and female participants. Clinically diagnosed chronic stroke (\>6 months post-onset). Impaired dynamic balance or mobility. Ability to follow simple verbal instructions and medically stable.

You may not qualify if:

  • Severe cognitive impairment preventing participation. Severe spasticity (Modified Ashworth Scale \>3). Other neurological or musculoskeletal conditions affecting balance. Uncontrolled cardiovascular conditions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stroke support foundation

Mingora, KPK, 19130, Pakistan

RECRUITING

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Physical therapist

CONTACT

923415026592behlol109@gmail.com

Somiya Naz, BSPT, PPDPT, PhD Scholar

CONTACT

923315163093dr.somiyanaz@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

October 14, 2026

First Posted

October 21, 2026

Study Start

July 25, 2026

Primary Completion (Estimated)

December 25, 2026

Study Completion (Estimated)

December 30, 2026

Last Updated

October 21, 2026

Record last verified: 2026-10

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)