Comparative Effects of Mirror Therapy, Proprioceptive Neuromuscular Facilitation, and Constraint-Induced Movement Therapy on Upper Limb Motor Recovery in Stroke Survivors: A Three-Arm Randomized Controlled Trial

NCT07683130 | Completed

• 1 other identifier: FMRL_02_26
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to compare the effects of these three interventions on upper limb motor recovery in stroke survivors. A three-arm randomized controlled trial was conducted in which eligible participants (N=90) with post-stroke upper limb hemiparesis were randomly allocated into three groups of 30 each: MT group, PNF group, and CIMT group. All groups received their respective interventions alongside conventional physiotherapy, five sessions per week for six weeks.

Conditions

Stroke

Keywords

Stroke, Mirror Therapy, Rehabilitation

Outcome Measures

Primary Outcomes (4)

• Action Research Arm Test

  The assessment were taken at baseline and after 12 weeks of intervention

  12 weeks

• Fugl-Meyer Assessment for Upper Extremity

  The assessment were taken at baseline and after 12 weeks of intervention

  12 weeks

• Modified Ashworth Scale

  The assessment were taken at baseline and after 12 weeks of intervention

  12 weeks

• grip strength via hand-held dynamometry

  The assessment were taken at baseline and after 12 weeks of intervention

  12 weeks

Study Arms (3)

Mirror Therapy

ACTIVE COMPARATOR

Other: mirror therapy

Proprioceptive Neuromuscular Facilitation

ACTIVE COMPARATOR

Other: PNF

Constraint-Induced Movement Therapy

ACTIVE COMPARATOR

Other: Constraint-induced movement therapy

Interventions

mirror therapy OTHER

Mirror Therapy: Participant in the group were provided mirror therapy for a duration of 12 weeks

Mirror Therapy

PNF OTHER

PNF Group: Participant were given PNF therapy for a total duration of 12 weeks

Proprioceptive Neuromuscular Facilitation

Constraint-induced movement therapy OTHER

Constraint-induced movement therapy: Participant were given Constraint-induced movement therapy for a total duration of 12 weeks

Constraint-Induced Movement Therapy

Eligibility Criteria

• Age: 25 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Stroke Patients Both male and female Age: 25-65 years -

You may not qualify if:

• unable to perform exercises Do not provide consent Cognitive Impairment

Sponsors & Collaborators

• Foundation of Medical Research and Laboratories, Pakistan: lead

Study Sites (1)

Ikram Hospital, Gujrat

Gujrat, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Stroke

Interventions

Mirror Movement Therapy; Constraint Induced Movement Therapy

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Physical Therapy Modalities; Rehabilitation; Therapeutics; Exercise Therapy

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 27, 2026
• First Posted: July 6, 2026
• Study Start: July 3, 2025
• Primary Completion: January 3, 2026
• Study Completion: January 3, 2026
• Last Updated: July 6, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)