Pragmatic Interventions to Advance Cancer Survivor Outcomes

NCT07886853 | Not Yet Recruiting DMC

• 1 other identifier: STU20260824
• Study Type: observational
• Target: 10,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this study is to learn how common medical decisions made during routine care-such as medications, exercise recommendations, referrals, and imaging-affect health outcomes.

Conditions

Cancer; Malignant Neoplasm

Outcome Measures

Primary Outcomes (1)

• Adverse Event occurrence

  Occurrence of any grade 2+ adverse event (heart failure, etc.) following cancer diagnosis, as identified through structured data.

  From time of consent up to 12 months

Secondary Outcomes (1)

• Change in cardiovascular risk factors

  From time of consent up to 12 months

Interventions

Clinical Care decisions OTHER

This registry will support observational comparative effectiveness analyses of pragmatic clinical decisions. Clinical care decisions, including medication use, referral patterns, exercise recommendations, and imaging strategies, will be made by treating clinicians independent of study participation. No investigational drug or device is being tested.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Study population includes participants that have a diagnosis of any malignant neoplasm and were treated at UTSW Comprehensive Cancer Center cancer clinics, cardio-oncology, or exercise oncology clinics. Receiving care in a participating UTSW cancer clinic or referred to these clinics.

You may qualify if:

• Adult patients (≥18 years).
• Diagnosis of any malignant neoplasm treated at UTSW Comprehensive Cancer Center cancer clinics, cardio-oncology and exercise oncology clinics
• Receiving care in a participating UTSW cancer clinic, or referred to these clinics.
• Able to provide informed consent, unless a waiver of consent is approved for retrospective data collection.
• Unknown/unclear or equivocal difference or lack of guideline in management strategy

You may not qualify if:

• Individuals unable to provide informed consent for prospective participation, unless a legally authorized representative process is approved.
• Pregnant individuals may be excluded from specific analyses involving procedures not appropriate during pregnancy.
• Patients whose records are subject to legal or institutional restrictions preventing research use.

Sponsors & Collaborators

• University of Texas Southwestern Medical Center: lead

MeSH Terms

Conditions

Neoplasms

Study Officials

• Daniel Addison, MD

  University of Texas Southwestern Medical Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Chinedu Agumadu

CONTACT

214-648-1634; Chinedu.Agumadu@UTSouthwestern.edu

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, Internal Medicine - Cardiology

Study Record Dates

• First Submitted: October 14, 2026
• First Posted: October 21, 2026
• Study Start (Estimated): November 1, 2026
• Primary Completion (Estimated): November 1, 2032
• Study Completion (Estimated): November 1, 2032
• Last Updated: October 21, 2026

Record last verified: 2026-10