Assessment of the Degree of Regeneration After Partial Meniscectomy Based on Thin-layer MRI Image Segmentation and Reconstruction

NCT07885943 | Recruiting

• 1 other identifier: 26045-4-01
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to employ 3.0T thin-slice high-resolution magnetic resonance imaging (MRI) and MIMICS image three-dimensionalreconstruction.Additionally, we examined the regeneration of the menisci in patients who had undergone partial meniscectomy of the knee joint at our hospital through retrospective follow-up and meniscus segmentation techniques. Proactive quantitative analysis of the meniscus in patients following partial meniscectomy of the knee joint 6 months and 12 months post-surgery. The relationship between the percentage of regenerated tissue and the location and extent of the surgical excision.

Conditions

Meniscus Regeneration; Partial Meniscectomy

Keywords

Meniscus regeneration; Magnetic Resonance Imaging (MRI); Three-dimensional reconstruction; Volume quantification; Cohort study.

Outcome Measures

Primary Outcomes (1)

• Percentage of regenerated volume of the partially resected meniscus after 6 months and 1 year post-surgery.

  Six months and one year post-surgery.

Secondary Outcomes (1)

• Knee joint function assessment score.

  Six months and one year post-surgery.

Study Arms (4)

Partial meniscectomy.

Patients who underwent partial meniscectomy at our hospital.

Other: No intervention measures.

Complete resection of the meniscus.

Patients who have undergone a complete resection of the meniscus due to a discoid meniscus or meniscal tear at our hospital.

Other: No intervention measures.

Complete resection of the meniscus + drilling of a bone channel.

Complete meniscectomy + anterior cruciate ligament reconstruction with drilling of an osteotomy channel.

Other: No intervention measures.

Partial meniscectomy + drilling of a bone channel.

Performed a partial meniscectomy + anterior cruciate ligament reconstruction with drilling of an osteotomy channel.

Other: No intervention measures.

Interventions

No intervention measures. OTHER

No intervention measures.

Complete resection of the meniscus + drilling of a bone channel.; Complete resection of the meniscus.; Partial meniscectomy + drilling of a bone channel.; Partial meniscectomy.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Research Subjects For patients who have undergone partial meniscectomy using arthroscopy at our hospital, as well as those planning to undergo a similar procedure at our facility. Patients who have undergone a surgical procedure.

You may qualify if:

• Patients who underwent partial resection of the meniscus using arthroscopy in our hospital and had follow-up thin-slice MRI scans within one week after surgery; no cases of joint infection, joint tumors, or other diseases were present.

You may not qualify if:

• Patients who did not undergo an MRI scan within one week after surgery for the removal of the inferior meniscus using arthroscopy, who had MRI scan contraindications or refused the procedure.
• Patients who underwent nuclear magnetic resonance (NMR) re-evaluation and had undergone surgery at least half a year prior to the commencement of this experiment.

Sponsors & Collaborators

• Beijing Tsinghua Chang Gung Hospital: lead

Study Sites (1)

Tsinghua Changgung Hospital, Beijing

Beijing, Beijing Municipality, 410006, China

RECRUITING

Central Study Contacts

Jiwen LONG

CONTACT

+86 13975982156; 1363477686@qq.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 14, 2026
• First Posted: October 21, 2026
• Study Start: January 1, 2024
• Primary Completion (Estimated): January 1, 2028
• Study Completion (Estimated): January 1, 2028
• Last Updated: October 21, 2026

Record last verified: 2026-10

Locations

CN (1)