27-Inch Versus 55-Inch Monitors in Women Undergoing Endometrial Cancer Surgery

NCT07882277 | Not Yet Recruiting

• 1 other identifier: 2024-KAEK-11-255
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

This study will compare the use of 27-inch and 55-inch endoscopic imaging monitors during minimally invasive surgery for women with endometrial cancer. Participants will be randomly assigned to one of the two monitor groups. All participants will undergo the same standard surgical procedure; only the monitor size used during surgery will differ. The main question is whether monitor size affects total operative time. The study will also evaluate sentinel lymph node dissection time, blood count changes, complications, infections, hospital stay, and drain-related outcomes during the first 30 days after surgery.

Conditions

Endometrial Cancer

Keywords

Minimally Invasive Surgery; Laparoscopy; Laparoscopic Hysterectomy; Sentinel Lymph Node Dissection; Endoscopic Imaging Monitor; Monitor Size

Outcome Measures

Primary Outcomes (1)

• Total Operative Time

  Total operative time, defined as the time from entry of the laparoscopic optic into the abdomen after trocar placement to completion of surgery, measured in minutes.

  During surgery

Secondary Outcomes (12)

• Bilateral Pelvic Sentinel Lymph Node Dissection Time

  During surgery

• Number of Retrieved Sentinel Lymph Nodes

  From surgery to final pathology assessment, up to 30 days after surgery

• Hemoglobin Decrease

  Preoperative to postoperative 24 hours

• Hematocrit Decrease

  Preoperative to postoperative 24 hours

• Blood Transfusion Requirement

  From start of surgery to hospital discharge, up to 30 days after surgery

Study Arms (2)

27-Inch Monitor Group

EXPERIMENTAL

Participants randomized to this arm will undergo minimally invasive endometrial cancer surgery using a 27-inch 4K-2D endoscopic imaging monitor. The surgical procedure and perioperative care will be standardized.

Device: 27-Inch Endoscopic Imaging Monitor

55-Inch Monitor Group

ACTIVE COMPARATOR

Participants randomized to this arm will undergo the same minimally invasive endometrial cancer surgery using a 55-inch 4K-2D endoscopic imaging monitor. The surgical procedure and perioperative care will be standardized.

Device: 55-Inch Endoscopic Imaging Monitor

Interventions

55-Inch Endoscopic Imaging Monitor DEVICE

Use of a 55-inch 4K-2D endoscopic imaging monitor during minimally invasive endometrial cancer surgery.

55-Inch Monitor Group

27-Inch Endoscopic Imaging Monitor DEVICE

Use of a 27-inch 4K-2D endoscopic imaging monitor during minimally invasive endometrial cancer surgery.

27-Inch Monitor Group

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Female patients aged 18 years or older
• Histologically diagnosed endometrial cancer with planned surgical treatment
• Eligible for minimally invasive surgery
• Planned total laparoscopic hysterectomy with bilateral salpingectomy or bilateral salpingo-oophorectomy and sentinel lymph node dissection
• No severe systemic disease that would contraindicate laparoscopic surgery based on preoperative evaluation
• Standard cervical four-quadrant indocyanine green injection planned for sentinel lymph node mapping
• Bilateral sentinel lymph node mapping and bilateral sentinel lymph node dissection feasible during surgery
• Preoperative hemoglobin level of 10 g/dL or higher
• Able and willing to provide written informed consent

You may not qualify if:

• Distant metastasis detected on preoperative imaging or clinical evaluation
• Not suitable for minimally invasive surgery, such as severe cardiopulmonary disease
• Conversion from laparoscopy to laparotomy
• Failure of bilateral sentinel lymph node mapping or inability to perform bilateral sentinel lymph node dissection
• Systematic pelvic and/or para-aortic lymph node dissection performed
• Body mass index of 40 kg/m² or higher
• Uterine size equivalent to 12 weeks of gestation or larger
• Dense bowel or omental adhesions detected intraoperatively
• History of abdominal surgery through a midline incision
• History of myomectomy
• History of tubo-ovarian abscess
• History of three or more cesarean deliveries
• Need for an additional major surgical procedure outside the standardized surgical protocol
• Preoperative hemoglobin level below 10 g/dL
• Refusal to participate or inability to provide informed consent

Sponsors & Collaborators

• Metehan Uzundal: lead

Study Sites (1)

Basaksehir Cam and Sakura City Hospital

Istanbul, Istanbul, 34480, Turkey (Türkiye)

Location

Related Publications (3)

• Walczak DA, Pawelczak D, Piotrowski P, Trzeciak PW, Jedrzejczyk A, Pasieka Z. Video display during laparoscopy - where should it be placed? Wideochir Inne Tech Maloinwazyjne. 2015 Apr;10(1):87-91. doi: 10.5114/wiitm.2014.47434. Epub 2014 Dec 4.

  PMID: 25960798 BACKGROUND

• El Shallaly G, Cuschieri A. Optimum view distance for laparoscopic surgery. Surg Endosc. 2006 Dec;20(12):1879-82. doi: 10.1007/s00464-005-0162-1.

  PMID: 17031749 BACKGROUND

• Sivas MC, Aslan Cetin B, Ohanoglu Cetinel K, Geyikoglu IE. The effect of using laparoscopic imaging screens of different sizes (55-inch vs. 27-inch) on surgical parameters in hysterectomy surgery: a retrospective cohort study. BMC Surg. 2025 Oct 3;25(1):425. doi: 10.1186/s12893-025-03168-1.

  PMID: 41044554 BACKGROUND

MeSH Terms

Conditions

Endometrial Neoplasms

Condition Hierarchy (Ancestors)

Uterine Neoplasms; Genital Neoplasms, Female; Urogenital Neoplasms; Neoplasms by Site; Neoplasms; Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Study Officials

• Metehan Uzundal, MD

  Başakşehir Çam & Sakura City Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Metehan Uzundal, MD

CONTACT

+90 541 291 23 88; metehan_uzndl@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants will be masked to the assigned monitor size. Surgeons, operating room staff, and investigators will not be masked because the assigned monitor must be visible and prepared before surgery.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Obstetrics and Gynecology Specialist, Gynecologic Oncology Fellow

Model Details: Participants will be randomly assigned in a 1:1 ratio to one of two parallel groups: surgery using a 27-inch endoscopic imaging monitor or surgery using a 55-inch endoscopic imaging monitor. The surgical procedure and perioperative care will be standardized across both groups.

Study Record Dates

• First Submitted: October 6, 2026
• First Posted: October 20, 2026
• Study Start: October 1, 2026
• Primary Completion (Estimated): January 1, 2028
• Study Completion (Estimated): February 1, 2028
• Last Updated: October 20, 2026

Record last verified: 2026-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)