Comparison of Spinal Anesthesia and General Anesthesia Plus Transversus Abdominis Plane Block in Laparoscopic Total Extraperitoneal Inguinal Hernia Repair: A Prospective Randomized Double-Blind Clinical Trial
Sponsor study identifier
interventional
70
1 country
1
Study Start
September 1, 2026
Actual (reported)Primary Completion
April 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
April 3, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
This prospective, randomized, double-blind clinical trial compares spinal anesthesia with general anesthesia combined with ultrasound-guided transversus abdominis plane (TAP) block in adult patients undergoing laparoscopic total extraperitoneal (TEP) inguinal hernia repair. Patients will be randomly assigned to one of two anesthesia groups. The primary outcome is postoperative pain assessed using the Visual Analog Scale (VAS) at 1 hour after surgery. Postoperative pain at additional time points, analgesic requirements, opioid consumption, and postoperative complications will also be evaluated.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 3, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 1, 2026
Actual (reported)October 5, 2026
Actual (reported)October 8, 2026
Actual (reported)April 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
April 3, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Postoperative Pain at 1 Hour
Postoperative pain intensity assessed using the Visual Analog Scale (VAS).
1 hour after surgery
Postoperative Pain at 4, 8, and 12 Hours
4, 8, and 12 hours after surgery
Postoperative Seroma
Within the first 24 hours after surgery
Patients in this group will undergo laparoscopic total extraperitoneal (TEP) inguinal hernia repair under general anesthesia combined with an ultrasound-guided transversus abdominis plane (TAP) block.
Patients in this group will undergo laparoscopic total extraperitoneal (TEP) inguinal hernia repair under spinal anesthesia.
General anesthesia will be administered according to the institutional standard protocol. Following induction of general anesthesia and before the surgical procedure, an ultrasound-guided TAP block will be performed under sterile conditions using a linear ultrasound probe. The fascial plane between the internal oblique and transversus abdominis muscles will be identified and local anesthetic will be administered according to the study protocol.
Bakırköy Dr. Sadi Konuk Training and Research Hospital
Istanbul, Istanbul, 34147, Turkey (Türkiye)
First Submitted
October 5, 2026
First Posted
October 8, 2026
Study Start
September 1, 2026
Actual (reported)Spinal anesthesia will be performed in the sitting position using a 25-gauge Quincke spinal needle after sterile preparation. Hyperbaric bupivacaine 0.5% (15 mg) with preservative-free fentanyl (10 µg) will be administered intrathecally according to the study protocol. Conscious sedation will be provided with midazolam, fentanyl, and propofol as required.
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Primary Completion
April 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
April 3, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
October 8, 2026
Record last verified: 2026-10
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Source: ClinicalTrials.gov.
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