NCT07861087|Completed
Influence of Vaccine Message Medium on Intentions to Vaccinate in College Students
Vaccination Visual Messaging and Intent to Vaccinate
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Vaccination Visual Messaging and Intent to Vaccinate
Sponsor study identifier
interventional
1,064
1 country
1
Study Start
September 27, 2023
Actual (reported)Primary Completion
November 1, 2023
Actual (reported)Study Completion
November 1, 2023
Actual (reported)The goal of this clinical trial is to understand the influence of vaccine message medium (e.g., text, photo, or video) on intentions to vaccinate in college students. The main question it aims to answer is:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 1, 2023
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 27, 2023
Actual (reported)November 1, 2023
Actual (reported)November 1, 2023
Actual (reported)September 25, 2026
Actual (reported)October 6, 2026
Actual (reported)Vaccine Intention
A measure of intention to receive the COVID-19 vaccine before and after receiving the intervention. On the individual vaccine intention scores \[1-5\], 1 is equivalent to strongly intending not to receive the vaccine, and 5 indicates a strong intention to receive the vaccine. A higher score is a better outcome, related to stronger intentions to receive the vaccine.
The outcome was measured immediately following the intervention in the online survey
Vaccine Intention Change
Using Vaccine Intention scores, we calculated the Vaccine Intention Change by finding the difference between intentions to vaccinate before and after viewing our intervention message. A change score \[0-4\] of 0 indicates no change in intention, while 4 indicates a large change in intention. Depending on the individual's initial Vaccine Intention Score, a large change score may indicate an increase or decrease in intentions to vaccinate.
The outcome was measured immediately following the intervention in the online survey
COVID-19 Threat
The outcome was measured immediately following the intervention in the online survey
This group received the poster message.
This group received the word message, a text-only intervention.
This group received the video message.
The video message also featured a man describing that he had received a COVID-19 vaccine and why he got vaccinated, again including information on the safety and efficacy of the vaccine. At the end of the video, he recommends using a "reliable source like the CDC website and get the facts."
The word-only message, inspired by both the video transcript and words on the poster, encourages vaccination and highlights the safety and widespread uptake of the vaccine. It also includes a recommendation to "get the facts" by visiting the CDC coronavirus vaccine webpage.
Department of Biology
State College, Pennsylvania, 16803, United States
Katie J Yan
Penn State University
1,064 participants (actual enrollment reported by the registry).
First Submitted
September 25, 2026
First Posted
October 6, 2026
Study Start
September 27, 2023
Actual (reported)Developing and Testing a COVID-19 Vaccination Acceptance Intervention
The poster message featured a man wearing two facemasks and showing off his upper arm with a band aid, indicating vaccination. Overlaid was the phrase "Protect Against COVID-19." as well as a short blurb describing the safety and efficacy of COVID-19 vaccines and a link to a CDC COVID-19 vaccine webpage.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
November 1, 2023
Actual (reported)Study Completion
November 1, 2023
Actual (reported)Last Updated
October 6, 2026
Record last verified: 2026-10
No plan to share individual participant data (IPD). Data sharing beyond the research team was not included in the informed consent obtained from participants, and the dataset carries reidentification risk given its detailed demographic and behavioral variables.
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Source: ClinicalTrials.gov.
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