Ultrasound Guided- Chemical Rectus Sheath Block for Chronic Pain After Abdominal Midline Incision in Cancer Surgeries

NCT07855380 | Recruiting

• 1 other identifier: 04-2026-300865
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to evaluate peri-operative analgesia efficacy of ultrasound guided transversalis fascia plane block in cancer patients undergoing inguinal lymph node dissection

Conditions

Chemical Rectus Sheath Block; Chronic Pain; Abdominal Midline Incision; Cancer Surgeries

Outcome Measures

Primary Outcomes (1)

• Degree of pain

  Each patient will be instructed about postoperative pain assessment with the numeric rating scale (NRS) score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable").

  24 hours postoperatively

Secondary Outcomes (5)

• Total fentanyl consumption

  Intraoperatively

• Total opioid consumption

  24 hours postoperatively

• Mean arterial pressure

  24 hours postoperatively

• Heart rate

  24 hours postoperatively

• Incidence of complications

  24 hours postoperatively

Study Arms (2)

Group 1

SHAM COMPARATOR

Patients will receive a sham block was performed using an equivalent volume of normal saline 0.9%.

Drug: Saline 0.9%

Group 2

EXPERIMENTAL

Patients will receive ultrasound guided transversalis fascia plane block.

Drug: Transversalis fascia plane block

Interventions

Saline 0.9% DRUG

Patients will receive a sham block was performed using an equivalent volume of normal saline 0.9%.

Group 1

Transversalis fascia plane block DRUG

Patients will receive ultrasound guided transversalis fascia plane block.

Also known as: 20 ml of bupivacaine 0.25%

Group 2

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• American Society of Anesthesiologists (ASA) class I and II.
• Age ≥ 18 and ≤ 65 Years.
• Cancer patients for inguinal lymph node dissection.
• Body mass index (BMI): \> 20 kg/m2 and \< 40 kg/m2.

You may not qualify if:

• Patient refusal.
• Local infection at the puncture site.
• Coagulopathies with platelet count below 50,000 or an INR\>1.6.
• Unstable cardiovascular disease.
• History of psychiatric and cognitive disorders.
• Patients allergic to medication used.

Sponsors & Collaborators

• National Cancer Institute, Egypt: lead

Study Sites (1)

Cairo University

Cairo, 12613, Egypt

RECRUITING

MeSH Terms

Conditions

Chronic Pain

Interventions

Sodium Chloride

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Chlorides; Hydrochloric Acid; Chlorine Compounds; Inorganic Chemicals; Sodium Compounds

Central Study Contacts

Ahmed S Abdelgalil, MD

CONTACT

00201098426689; ahmed.salah@nci.cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Anaesthesia and Pain Medicine National Cancer, Cairo University.

Study Record Dates

• First Submitted: September 28, 2026
• First Posted: October 2, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: October 2, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)