Cancer Pain 101: A Digital, Asynchronous Intervention of Pain Management in Advanced Cancer
COPES Aim 3
2 other identifiers
interventional
45
1 country
1
Brief Summary
This is a Stage 1 study of a behavioral intervention, which means that a new intervention is being pilot tested to understand whether it is acceptable and feasible for people with advanced cancer to use. The purpose of this study is to evaluate whether a series of 3 10-minute videos may help improve prescription opioid pain management and opioid stigma for people living with advanced cancer. Approximately 45 participants will take part in this study at the University of Alabama at Birmingham. People who choose to participate in this study will complete a series of baseline questionnaires, and then will be randomized to one of two groups: 1) the group that gets the video intervention, or 2) the group that gets a written handout with information about cancer pain. About 4 weeks later, all participants will also be asked to fill out another series of questionnaires.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable cancer
Started Oct 2026
Shorter than P25 for not_applicable cancer
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 23, 2026
CompletedFirst Posted
Study publicly available on registry
October 1, 2026
CompletedStudy Start
First participant enrolled
October 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 1, 2027
October 1, 2026
September 1, 2026
6 months
September 23, 2026
September 23, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Participants who watch at least one video
Count participants who watch at least one video
4 weeks
Study Arms (2)
Intervention
EXPERIMENTALParticipants randomized to the intervention group will have access to three 10-minute videos through a digital application. The videos cover cancer pain, pain medications, and pain self-management skills, and will be available for four weeks.
Educational Control
NO INTERVENTIONParticipants in the educational control condition will receive a written handout about cancer pain, which is widely available and published by the American Cancer Society; they will not have access to the intervention videos.
Interventions
The study intervention is Cancer Pain 101. Cancer Pain 101 is a 3-part educational video series, designed to be delivered asynchronously. Each video is approximately 10 minutes long and is narrated by a multidisciplinary team, including a psychologist, oncologist, palliative care clinician, and pharmacist.
Eligibility Criteria
You may qualify if:
- age ≥ 18 years old
- speaks English
- current, advanced solid tumor cancer diagnosis (stage III or IV)
- endorses cancer-related pain (e.g,. pain, that began, worsened, and/or changed during cancer)
- current opioid prescription OR planning to initiate opioids for cancer pain management
You may not qualify if:
- observable psychiatric disorders that would interfere with study participation (e.g., dementia, psychosis)
- inability to speak and read English
- inability to provide informed consent
- prior participation in aspects of this study (i.e., K08 Aims 1 and 2)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
Related Publications (2)
Bulls HW, Hamm M, Wasilko R, de Abril Cameron F, Belin S, Goodin BR, Liebschutz JM, Wozniak A, Sabik LM, Merlin JS, Schenker Y. Manifestations of Opioid Stigma in Patients With Advanced Cancer: Perspectives From Patients and Their Support Providers. JCO Oncol Pract. 2022 Oct;18(10):e1594-e1602. doi: 10.1200/OP.22.00251. Epub 2022 Jul 25.
PMID: 35878073BACKGROUNDBulls HW, Chu E, Goodin BR, Liebschutz JM, Wozniak A, Schenker Y, Merlin JS. Framework for opioid stigma in cancer pain. Pain. 2022 Feb 1;163(2):e182-e189. doi: 10.1097/j.pain.0000000000002343.
PMID: 34010940BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Hailey W Bulls, PhD
University of Alabama at Birmingham
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
September 23, 2026
First Posted
October 1, 2026
Study Start
October 1, 2026
Primary Completion (Estimated)
April 1, 2027
Study Completion (Estimated)
May 1, 2027
Last Updated
October 1, 2026
Record last verified: 2026-09
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF
The proposed research will include data from a total of 120 patients (75 Aims 1 and 2; 45 Aim 3) with advanced cancer. The final dataset will include self-reported demographic data and survey data from pilot trial assessments. All data in our analysis will be deidentified. No identifying information will be retained past the conclusion of the K08 study period. The data collected will be used for publication purposes and will be made available for public use upon completion of our study and the initial dissemination of our research results. Any data shared will be de-identified.