Partial Digitalization of Mission ReST

NCT07851792 | Not Yet Recruiting

• 1 other identifier: HSEARS20251216001
• Study Type: interventional
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this non-randomized trial is to partially digitalize and develop a web-based resilience-building intervention and pilot-test its feasibility, acceptability, and appropriateness in an undergraduate sample over a 6-month implementation period. The main questions it aims to answer are:

• What are the rates of recruitment, adoption, and full program completion?
• What is the intervention's overall effectiveness in enhancing resilience and mental health outcomes? Researchers will compare the partially digitalized intervention with a structurally equivalent in-person mode of delivery.

Conditions

Resilience

Outcome Measures

Primary Outcomes (2)

• Feasibility of the digitalized individual components

  Proportion of eligible individuals who consent, participate, and complete the intervention

  From baseline to end of intervention at 6 weeks

• Acceptability of the digitalized individual components

  Quantitative measure of participant satisfaction based on a 5-point Likert scale ranging from "1=Very Dissatisfied" to "5=Very Satisfied," and qualitative description of participants' perspectives on acceptability of the intervention.

  From baseline to end of intervention at 6 weeks

Secondary Outcomes (3)

• Resilience

  From baseline to end of follow-up assessment at 10 weeks

• Depression, anxiety, and stress

  From baseline to end of follow-up assessment at 10 weeks

• Disturbances in self-organization

  From baseline to end of follow-up assessment at 10 weeks

Study Arms (2)

Digitalized, AI-based web app

EXPERIMENTAL

In the experimental arm, materials of the resilience-building psychoeducation are delivered through an interactive web app. Based on users' assessment responses (i.e., multiple choice and free-text questions), an integrated AI-based recommender system using a hybrid filtering approach will identify and deliver suitable resilience-building strategies.

Behavioral: Digitalized Session 1 of Mission ReST

In-person delivery

ACTIVE COMPARATOR

In the active comparator arm, the structurally and time-equivalent modules are delivered by trained facilitators.

Behavioral: In-person delivery of Mission ReST Session 1

Interventions

Digitalized Session 1 of Mission ReST BEHAVIORAL

The interactive web app is integrated with an AI-based recommender system using a hybrid filtering approach that will identify and deliver suitable strategies based on users' assessment responses (i.e., multiple choice and free-text questions).

Digitalized, AI-based web app

In-person delivery of Mission ReST Session 1 BEHAVIORAL

Structurally and time equivalent to the digital version of Mission ReST Session 1, delivered by a trained facilitator after assessing the participant's concerns and responses.

In-person delivery

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Undergraduate at PolyU
• Able to provide informed consent
• Report normal to moderate levels of distress as measured by DASS-21

You may not qualify if:

• Severe or higher levels of mental distress as measured by DASS-21
• Self-report diagnosis of mental illness
• Currently receiving professional mental health services

Sponsors & Collaborators

• The Hong Kong Polytechnic University: lead

Study Sites (1)

School of Nursing, The Hong Kong Polytechnic University

Hong Kong, Hong Kong

Location

Related Publications (11)

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  PMID: 30178492 BACKGROUND

• Handley MA, Lyles CR, McCulloch C, Cattamanchi A. Selecting and Improving Quasi-Experimental Designs in Effectiveness and Implementation Research. Annu Rev Public Health. 2018 Apr 1;39:5-25. doi: 10.1146/annurev-publhealth-040617-014128. Epub 2018 Jan 12.

  PMID: 29328873 BACKGROUND

• Hedberg EC, Ayers S. The power of a paired t-test with a covariate. Soc Sci Res. 2015 Mar;50:277-91. doi: 10.1016/j.ssresearch.2014.12.004. Epub 2014 Dec 17.

  PMID: 25592936 BACKGROUND

• Ho GWK, Karatzias T, Cloitre M, Chan ACY, Bressington D, Chien WT, Hyland P, Shevlin M. Translation and validation of the Chinese ICD-11 International Trauma Questionnaire (ITQ) for the Assessment of Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). Eur J Psychotraumatol. 2019 May 15;10(1):1608718. doi: 10.1080/20008198.2019.1608718. eCollection 2019.

  PMID: 31143410 BACKGROUND

• Smith BW, Dalen J, Wiggins K, Tooley E, Christopher P, Bernard J. The brief resilience scale: assessing the ability to bounce back. Int J Behav Med. 2008;15(3):194-200. doi: 10.1080/10705500802222972.

  PMID: 18696313 BACKGROUND

• Henry JD, Crawford JR. The short-form version of the Depression Anxiety Stress Scales (DASS-21): construct validity and normative data in a large non-clinical sample. Br J Clin Psychol. 2005 Jun;44(Pt 2):227-39. doi: 10.1348/014466505X29657.

  PMID: 16004657 BACKGROUND

• Achilles MR, Anderson M, Li SH, Subotic-Kerry M, Parker B, O'Dea B. Adherence to e-mental health among youth: Considerations for intervention development and research design. Digit Health. 2020 May 21;6:2055207620926064. doi: 10.1177/2055207620926064. eCollection 2020 Jan-Dec.

  PMID: 32547775 BACKGROUND

• Karatzias T, Mc Glanaghy E, Cloitre M. Enhanced Skills Training in Affective and Interpersonal Regulation (ESTAIR): A New Modular Treatment for ICD-11 Complex Posttraumatic Stress Disorder (CPTSD). Brain Sci. 2023 Sep 9;13(9):1300. doi: 10.3390/brainsci13091300.

  PMID: 37759901 BACKGROUND

• Abulfaraj GG, Upsher R, Zavos HMS, Dommett EJ. The Impact of Resilience Interventions on University Students' Mental Health and Well-Being: A Systematic Review. Educ Sci. 2024;14(5)doi:10.3390/educsci14050510

  BACKGROUND

• Ang WHD, Lau ST, Cheng LJ, et al. Effectiveness of resilience interventions for higher education students: A meta-analysis and metaregression. J Educ Psychol. 2022;114(7):1670-1694. doi:10.1037/edu0000719

  BACKGROUND

• Masten AS, Lucke CM, Nelson KM, Stallworthy IC. Resilience in Development and Psychopathology: Multisystem Perspectives. Annu Rev Clin Psychol. 2021 May 7;17:521-549. doi: 10.1146/annurev-clinpsy-081219-120307. Epub 2021 Feb 3.

  PMID: 33534615 BACKGROUND

Study Officials

• Grace WK Ho, PhD

  The Hong Kong Polytechnic University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Bryan Yu, PhD

CONTACT

+852 27666541; bryan-hw.yu@polyu.edu.hk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: A Pragmatic, Preference-Based, Open-Label, Non-Randomized Trial

Study Record Dates

• First Submitted: July 17, 2026
• First Posted: October 1, 2026
• Study Start (Estimated): November 1, 2026
• Primary Completion (Estimated): June 30, 2027
• Study Completion (Estimated): June 30, 2027
• Last Updated: October 1, 2026

Record last verified: 2026-09

Locations

HK (1)