Validity and Reliability of the Greek Pain Catastrophizing Scale

NCT07847528 | Not Yet Recruiting

• 1 other identifier: Approval Νο: 701, 3-6-2026
• Study Type: observational
• Target: 130
• Locations: 1 country
• Sites: 1

Brief Summary

Migraine is a common neurological disorder that can significantly affect daily activities, quality of life, and emotional well-being. How individuals think and feel about pain may also influence their experience of migraine. Pain catastrophizing refers to an exaggerated negative response to pain, including persistent worry about pain and feelings of helplessness. The Pain Catastrophizing Scale (PCS) is a commonly used questionnaire for assessing pain catastrophizing. However, the psychometric properties of the Greek version of the PCS have not been adequately evaluated in people with migraine. This study aims to evaluate the validity and reliability of the Greek version of the Pain Catastrophizing Scale in patients with migraine. The study will determine whether the Greek PCS can be used as an appropriate tool for assessing pain catastrophizing in the Greek migraine population.

Conditions

Migraine

Keywords

migraine; headache; pain catastrophizing; disability; quality of life; headache intensity

Outcome Measures

Primary Outcomes (1)

• Pain Catastrophizing Scale

  The psychometric properties of the Greek version of the Pain Catastrophizing Scale (PCS) will be evaluated in patients with migraine. The PCS consists of 13 items scored from 0 (never) to 4 (always), with a total score ranging from 0 to 52. Higher scores indicate greater pain catastrophizing. Reliability will be assessed using internal consistency and test-retest reliability.

  Baseline and 7-14 days after baseline for test-retest reliability.

Secondary Outcomes (4)

• Migraine Disability Assessment

  Baseline

• Headache Impact

  Baseline

• Migraine-Specific Quality of Life

  Baseline

• Headache Pain Intensity

  Baseline

Study Arms (1)

Patients with Migraine

Adults aged 18-70 years with a diagnosis of episodic or chronic migraine according to the International Classification of Headache Disorders, 3rd edition (ICHD-3), who are able to understand, read, write, and speak Greek. Participants will complete the Greek version of the Pain Catastrophizing Scale (PCS) and other study questionnaires for psychometric evaluation. No intervention will be administered.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of adults aged 18-70 years with episodic or chronic migraine diagnosed by a neurologist according to the International Classification of Headache Disorders, 3rd edition (ICHD-3). Participants will be recruited from the Headache Outpatient Clinic of Aeginition Hospital, National and Kapodistrian University of Athens, Greece. Eligible participants must be able to understand, read, write, and speak Greek.

You may qualify if:

• Diagnosis of migraine
• Age 18-70 years
• Ability to understand, read, write, and speak the Greek language

You may not qualify if:

• Presence of a headache disorder other than migraine
• History of systemic diseases (malignant, inflammatory, acute traumatic, infectious, surgical, neurological, psychiatric, or rheumatological conditions)

Sponsors & Collaborators

• National and Kapodistrian University of Athens: lead

Study Sites (1)

National Kapodistrian University of Athens, Aeginition Hospital, Headache Clinic

Athens, Attica, 11528, Greece

Location

Related Publications (18)

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MeSH Terms

Conditions

Migraine Disorders; Headache

Condition Hierarchy (Ancestors)

Headache Disorders, Primary; Headache Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Michalis Kodounis, Neurologist, PhD

CONTACT

+30 697 3600069; kodounis@gmail.com

Dimos Mitsikostas, Neurologist, PhD

CONTACT

dimosmitsikostas@me.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Week
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD, Neurologist, Medical Doctor

Study Record Dates

• First Submitted: September 22, 2026
• First Posted: September 29, 2026
• Study Start: September 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): July 1, 2027
• Last Updated: September 29, 2026

Record last verified: 2026-09

Locations

GR (1)