Changes in Physical Activity, Sleep and Knee Function After Same-Day Discharge Knee Arthroplasty
ORTOMOVE
ORTOMOVE: Protocol for a Prospective Cohort Study Comparing Physical Activity, Sleep Quality and Patient-reported Outcomes Following Same- Day Discharge Knee Arthroplasty
1 other identifier
observational
120
1 country
2
Brief Summary
The goal of this observational study is to examine changes in physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes before and after same-day discharge knee arthroplasty (SDD-KA). The study will also investigate whether these changes are associated with each other and with patient satisfaction. As a prespecified secondary aim, researchers will compare these outcomes between patients undergoing medial unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA). The main questions it aims to answer are:
- How do physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes change following SDD-KA?
- Are changes in these outcomes associated with each other and with patient satisfaction?
- Are these outcomes different between patients undergoing medial UKA and TKA? Participants will:
- Wear an accelerometer to measure physical activity and sleep before surgery, continuously from surgery to 3 months after surgery, and again for 2 weeks at 12 months after surgery
- Complete questionnaires about knee function, sleep quality, pain, health-related quality of life, and satisfaction with surgery
- Have knee muscle strength and active knee range of motion assessed before and 12 months after surgery
- Attend follow-up assessments during the 12-month postoperative period
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Aug 2025
Typical duration for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2025
CompletedFirst Submitted
Initial submission to the registry
September 18, 2026
CompletedFirst Posted
Study publicly available on registry
September 25, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2029
ExpectedStudy Completion
Last participant's last visit for all outcomes
February 1, 2029
September 25, 2026
September 1, 2026
3.5 years
September 18, 2026
September 18, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Oxford Knee Score (OKS)
A 12-item patient-reported questionnaire assessing knee pain and function during daily activities. Each item is scored from 0 to 4, giving a total score ranging from 0 to 48. Higher scores indicate better knee function and less pain.
The OKS will be completed by participants at baseline before surgery and at 3 and 12 months after surgery. The primary outcome is the change in OKS from baseline to 12 months after surgery.
Secondary Outcomes (8)
Objectively measured physical activity (sensor)
Measurements will be performed during a two-week period before surgery, continuously from surgery to 3 months postoperatively, and during a further two-week period at 12 months after surgery.
Objectively measured sleep (sensor)
Measurements will be performed during a two-week period before surgery, continuously from surgery to 3 months postoperatively, and during a further two-week period at 12 months after surgery.
Isometric knee extension and flexion strength
Measurements will be performed before surgery and at 12 months after surgery.
Knee range of motion
Measurements will be performed before surgery and at 12 months after surgery.
Jenkins Sleep Scale (JSS)
The JSS will be completed at 2 weeks preoperatively and 12 months postoperatively.
- +3 more secondary outcomes
Study Arms (2)
Medial unicompartmental knee arthroplasty (UKA)
Patients undergoing primary same-day discharge medial unicompartmental knee arthroplasty (UKA) for knee osteoarthritis. The medial UKA group will include 30 participants. The surgical procedure is determined by the treating clinical team according to established clinical indications and is not assigned by the study.
Total Knee Arthroplasty (TKA)
Patients undergoing primary same-day discharge total knee arthroplasty (TKA) for knee osteoarthritis. The TKA group will include 90 participants. The surgical procedure is determined by the treating clinical team according to established clinical indications and is not assigned by the study.
Interventions
Primary medial UKA performed as part of routine clinical care for knee osteoarthritis. The procedure is not assigned by the study.
Primary TKA performed as part of routine clinical care for knee osteoarthritis. The procedure is not assigned by the study.
Eligibility Criteria
The study population consists of patients undergoing same-day discharge primary knee arthroplasty: medial UKA or TKA according to standard clinical practice at Turku University Hospital. The choice of procedure is made on clinical grounds by the treating surgeon and is not influenced by study participation. Operations are performed by experienced arthroplasty surgeons under spinal anaesthesia following the hospital's standardized same-day discharge protocol.
You may qualify if:
- \- Primary knee osteoarthritis: medial or lateral Kellgren Lawrence grade 3-4 for TKA and antero-medial grade 3-4 for UKA.
- Patient criteria for outpatient knee arthroplasty (UKA or TKA):
- Full overnight support by an adult at home after discharge
- At most mild, well-controlled, comorbidities (e.g. hypertension, hypothyroidism, epilepsy, asthma)
- ASA-class 1-2
- Age \<80 years
- BMI \<35 kg/m2
You may not qualify if:
- Post-traumatic osteoarthritis
- Neurological disorder aVecting walking or muscle strength
- Inability or unwillingness to use a smartphone or to participate in the study
- History of cardiac or cerebrovascular events
- Conditions affecting consciousness (e.g. syncope of cardiac origin)
- Untreated or central sleep apnoea
- Heart failure
- Diabetes mellitus type 1
- Cognitive impairment or dementia
- History of substance abuse
- Chronic strong opioid therapy or severe pain disorder
- Antithrombotic therapy (e.g. Xarelto, Pradaxa, Plavix or ASA for secondary prevention)
- History of venous thromboembolism or known coagulopathy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Turku University Hospitallead
- UKK Institutecollaborator
Study Sites (2)
The UKK Institute for Health Promotion Research
Tampere, Finland
Turku University Hospital
Turku, Finland
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Ville Äärimaa, Title of Docent
Turku University Hospital
- STUDY CHAIR
Keijo Mäkelä, Professor
Turku University Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PhD student
Study Record Dates
First Submitted
September 18, 2026
First Posted
September 25, 2026
Study Start
August 1, 2025
Primary Completion (Estimated)
February 1, 2029
Study Completion (Estimated)
February 1, 2029
Last Updated
September 25, 2026
Record last verified: 2026-09
Data Sharing
- IPD Sharing
- Will not share
There is currently no plan to make individual participant data (IPD) available to other researchers. The study will collect individual-level clinical, patient-reported, and wearable sensor data, and any sharing of such data would be subject to applicable data protection requirements, ethical considerations, and institutional policies.