Circadian Rhythm and Cardiovascular Recovery After Submaximal Exercise

NCT07833956 | Not Yet Recruiting

• 1 other identifier: TopkapıUniver
• Study Type: observational
• Target: 124
• Locations: 1 country
• Sites: 1

Brief Summary

This cross-sectional, observational, and analytical study aims to investigate the relationship between morningness-eveningness characteristics and cardiovascular recovery after a submaximal exercise test in healthy individuals aged 18-45 years. Circadian preference will be assessed using the Morningness-Eveningness Questionnaire, sleep quality will be assessed using the Pittsburgh Sleep Quality Index, and cardiovascular recovery will be evaluated following the 6-Minute Walk Test

Conditions

Circadian Rhythm; Health Adult Subjects

Keywords

Circadian Rhythm; Cardiovascular Recovery; Submaximal Exercise Test

Outcome Measures

Primary Outcomes (1)

• Heart Rate Recovery After the 6-Minute Walk Test

  Heart rate will be recorded at rest, immediately after the 6-Minute Walk Test, and at the 1st, 3rd, and 5th minutes of the recovery period to evaluate cardiovascular recovery following submaximal exercise.

  Baseline and up to 5 minutes post-exercise

Secondary Outcomes (4)

• Oxygen Saturation (SpO₂) During Post-Exercise Recovery

  Up to 5 minutes after the 6-Minute Walk Test

• Borg Dyspnea/Fatigue Score During Post-Exercise Recovery

  Baseline and up to 5 minutes post-exercise

• Morningness-Eveningness Characteristics

  Baseline

• Sleep Quality

  Baseline

Study Arms (1)

Single Group

Healthy volunteers aged 18-45 years. Participants will complete a sociodemographic information form, the Morningness-Eveningness Questionnaire, and the Pittsburgh Sleep Quality Index. Resting heart rate, oxygen saturation, and Borg dyspnea/fatigue scores will be recorded, followed by the 6-Minute Walk Test. Physiological measurements will also be obtained immediately after the test and at the 1st, 3rd, and 5th minutes of recovery. No intervention will be administered

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Healthy volunteers aged 18-45 years who meet the study eligibility criteria and agree to participate voluntarily.

You may qualify if:

• Aged 18-45 years.
• Being healthy.
• Voluntarily agreeing to participate in the study.

You may not qualify if:

• Presence of cardiovascular, pulmonary, neurological, or orthopedic disease.
• Having a health problem that prevents exercise.
• Use of medication that may affect exercise tolerance.
• Pregnancy.

Sponsors & Collaborators

• Saglik Bilimleri Universitesi: lead

Study Sites (1)

İstanbul Topkapı University

Istanbul, Turkey (Türkiye)

Location

Study Officials

• Gamze Koyutürk, Asst Prof

  Topkapı University

  PRINCIPAL INVESTIGATOR

• Mehmet B Uyaroğlu, Asst Prof

  Fenerbahce University

  STUDY DIRECTOR

• Beyza Erdoğmuş, Dr

  STUDY CHAIR

• Hüsna Güzel, MsC

  Fenerbahce University

  STUDY CHAIR

Central Study Contacts

Gamze Koyutürk, Asst Prof

CONTACT

+905065798671; gamzealtinkaynak@gmail.com

Mehmet Burak Uyaroğlu, Asst Prof

CONTACT

5396545352; m.uyaroglu1@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: September 16, 2026
• First Posted: September 22, 2026
• Study Start: October 1, 2026
• Primary Completion (Estimated): March 31, 2027
• Study Completion (Estimated): March 31, 2027
• Last Updated: September 22, 2026

Record last verified: 2026-09

Locations

TU (1)