BioNortHealth Project

NCT07833787 | Recruiting

• 2 other identifiers: CE0081F09/C06-i07/2024.P11721
• Study Type: observational
• Target: 1,500
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational longitudinal cohort study is to identify key lifestyle-related predictors of health and disease and to understand how health trajectories develop over time in adolescents and young adults. The main questions it aims to answer are:

• How are lifestyle habits associated with health indicators in adolescents and young adults?
• Which individual, social, and environmental factors act as risk or protective determinants of health over time?
• How do lifestyle behaviours and health determinants evolve during critical life transitions, particularly academic transitions? What causal relationships exist between changes in lifestyle habits and health outcomes, after controlling for potential confounders? Participants will:
• Provide digital health and lifestyle data through a digital biobank platform;
• Be followed longitudinally with repeated data collection over time;
• Contribute information related to health status, lifestyle behaviours, and individual, social, and environmental determinants.

Conditions

College Students

Keywords

Lifestyle; Cohort Study; Digital Health; Public Health

Outcome Measures

Primary Outcomes (46)

• Food Propensity Questionnaire

  Food Propensity Questionnaire is a self-report instrument used within the scope of the National Food and Physical Activity Survey (IAN-AF, Portugal), designed to assess the habitual frequency of food consumption. The questionnaire aims to characterise participants' dietary patterns based on a typical week over the previous 12 months, allowing for an estimation of habitual intake throughout the year.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Alcohol, Smoking and Substance Involvement Screening Test (ASSIST v3.1)

  The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST), version 3.1, is a self-report screening instrument developed by the World Health Organization to detect and manage substance use and related risks. The ASSIST assesses lifetime and recent (past three months) use of a range of psychoactive substances, including tobacco, alcohol, cannabis, cocaine, stimulants, inhalants, sedatives, hallucinogens, opioids, and other substances.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Substance Use Questionnaire

  The Substance Use Questionnaire is a self-report instrument that assesses lifetime and current use of tobacco, vaping, and recreational drugs, including patterns, quantity, and history of consumption.

  Baseline, Year 3, Year 5

• Sexual Health Questionnaire

  The Sexual Health Questionnaire is a self-report instrument that assesses sexual history and sexual health characteristics.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Sexual Risk Behaviours Questionnaire

  The Sexual Risk Behaviours Questionnaire is a self-report instrument that assesses the frequency of sexual risk behaviours over the past month, including unprotected sexual practices, substance use during sexual activity, number and type of partners, and sexually transmitted infection testing.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Sexually Transmitted Diseases Knowledge Questionnaire (STD-KQ)

  The Sexually Transmitted Diseases Knowledge Questionnaire is a self-report instrument that assesses knowledge about sexually transmitted infections, including transmission, prevention, symptoms, treatment, and vaccination.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Health-Promoting Lifestyle Profile-II (HPLP-II)

  The Health-Promoting Lifestyle Profile-II is a self-report questionnaire assessing the frequency of health-promoting behaviors across physical, social, and psychological domains.

  Baseline, Year 3, Year 5

• Plastics and Human Health

  The Plastics and Human Health was developed with the aim of assessing potential sources of human exposure to microplastics associated with dietary habits, beverage consumption, lifestyle, and daily contact with plastic materials.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Exposure to Obesogenic Compounds (OBECARE)

  The Exposure to Obesogenic Compounds questionnaire is a self-report tool designed to assess daily exposure to obesogenic compounds from food, environment, and personal care products, which may affect metabolic health and contribute to obesity risk.

  Baseline, Year 4

• International Physical Activity Questionnaire - Short Form (IPAQ-SF)

  International Physical Activity Questionnaire - Short Form is questionnaire to assess self-reported physical activity.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Epworth Sleepiness Scale (ESS)

  The Epworth Sleepiness Scale is a self-report questionnaire measuring the likelihood of dozing off in daily situations, assessing habitual daytime sleepiness.

  Baseline, Year 3, Year 5

• Multidimensional Scale of Perceived Social Support (MSPSS)

  The Multidimensional Scale of Perceived Social Support is a self-report questionnaire assessing perceived social support from family, friends, and significant others, using a 7-point agreement scale.

  Baseline, Year 3, Year 5

• Medication and Supplementation Questionnaire (MSQ)

  The Medication and Supplementation Questionnaire is a self-report tool for recording all medications and dietary supplements taken in the past week, including reason for use and source of guidance (physician, other health professional, or self-medication).

  Baseline, Year 2, Year 3, Year 4, Year 5

• Measure of Treatment Adherence (MAT)

  The Measure of Treatment Adherence is a self-report instrument developed to assess the degree of patients' adherence to prescribed pharmacological therapy.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Depression, Anxiety, And Stress Scale - 21 (DASS-21)

  The Depression, Anxiety, And Stress Scale - 21 is a 21-item self-report scale measuring depression, anxiety, and stress, with seven items per subscale.

  Baseline, Year 2, Year 3, Year 4, Year 5

• World Health Organization-Five Well-Being Index (WHO-5)

  The World Health Organization-Five Well-Being Index is a 5-item self-report scale assessing subjective well-being over the past two weeks, with higher scores indicating greater well-being.

  Baseline, Year 3, Year 5

• Warwick Edinburgh Mental Well Being Scale (WEMWBS)

  The Warwick Edinburgh Mental Well Being Scale is a self-report scale measuring positive mental well-being over the past two weeks, covering thoughts, feelings, and social connectedness.

  Baseline, Year 3, Year 5

• Adapted Graffar Scale

  The Adapted Graffar Scale is used to assess and classify the socioeconomic level of a household.

  Baseline, Year 2, Year 3, Year 4, Year 5

• Female Sexual Function Index- 6 (FSFI-6)

  The Female Sexual Function Index- 6 is a 6-item self-report questionnaire assessing female sexual function over the past four weeks, covering desire, arousal, lubrication, orgasm, satisfaction, and pain.

  Year 2, Year 4

• International Index of Erectile Function (IIEF-5)

  The International Index of Erectile Function is a 5-item self-report questionnaire assessing erectile function over the past six months, including confidence, erection quality, maintenance, and sexual satisfaction.

  Year 2, Year 4

• Pittsburgh Sleep Quality Index (PSQI)

  The Pittsburgh Sleep Quality Index is a self-report questionnaire assessing sleep quality and disturbances over the past month, including sleep duration, latency, efficiency, disturbances, medication use, and daytime dysfunction.

  Year 2, Year 4

• Digital and Social Habits

  Is a self-report questionnaire assessing digital and social media habits, including frequency and purpose of internet and social media use, digital literacy, use of artificial intelligence and smart technologies, privacy concerns, and daily screen time.

  Year 2, Year 4

• Digital Habits

  This self-report questionnaire measures daily digital habits, including time spent on smartphones, social media, video games, non-digital games, types of games, and digital study.

  Year 2, Year 4

• SUSceptibility to being Influenced by Social media Influencers (SUSIS)

  The SUSceptibility to being Influenced by Social media Influencers is a self-report questionnaire developed to assess the degree of individuals' susceptibility to the influence exerted by social media influencers.

  Year 2, Year 4

• Internet Severity and Activities Questionnaire (ISAAQ-10)

  The Internet Severity and Activities Questionnaire is a 10-item self-report questionnaire assessing problematic internet use over the past six months, including time management, emotional regulation, neglect of daily activities, preoccupation, sleep disruption, and related physical or psychological problems.

  Year 2, Year 4

• Cyberbullying Perpetration and Victimization Scales (CBV)

  The Cyberbullying Perpetration and Victimization Scales questionnaire measures participants' experiences of being victims of cyberbullying. It assesses how often individuals are exposed to harmful or aggressive behaviours through online platforms such as social media, messaging apps, and other digital communication tools.

  Year 2, Year 4

• Healthy Lifestyle - Natural Environments

  The Healthy Lifestyle - Natural Environments questionnaire assesses frequency of visits to blue and green spaces, reasons for visiting, daily exposure, and views from home to evaluate engagement with natural environments.

  Year 2, Year 4

• Patient Health Questionnaire-9 (PHQ-9)

  The Patient Health Questionnaire is a 9-item self-report scale assessing the severity of depressive symptoms over the past two weeks and their impact on daily functioning.

  Year 2, Year 4

• Community Assessment of Psychic Experiences-42 (CAPE-42)

  The Community Assessment of Psychic Experiences (CAPE-42) is a self-report questionnaire assessing the lifetime frequency and associated distress of psychotic-like experiences across positive, negative, and depressive dimensions.

  Year 2

• Trauma History Questionnaire (THQ)

  The Trauma History Questionnaire is a self-report tool assessing lifetime exposure to traumatic events, including crime, disasters, and physical or sexual experiences. It records occurrence, frequency, and age at exposure.

  Year 2, Year 4

• Reading the Mind in the Eyes Test (RMET)

  The Reading the Mind in the Eyes Test measures the ability to recognize others' emotions and mental states from images of their eyes.

  Year 2

• Mental Health-Promoting Knowledge Measure (MHPK-10)

  The Mental Health-Promoting Knowledge Measure assesses understanding of factors important for good mental health through 10 statements.

  Year 2, Year 4

• Interoceptive Accuracy Scale (IAS)

  The Interoceptive Accuracy Scale measures how well people notice their bodily sensations, like heartbeat, hunger, thirst, or pain.

  Year 2, Year 4

• Interoceptive Attention Scale (IATS)

  The Interoceptive Attention Scale measures how much people pay attention to their body sensations, like heartbeat, hunger, thirst, or pain.

  Year 2, Year 4

• Reported and Intended Behavior Scale (RIBS)

  The Reported and Intended Behavior Scale is a brief self-report questionnaire assessing current and intended behaviors toward people with mental health problems, focusing on stigma and discriminatory attitudes.

  Year 2, Year 4

• Autism Spectrum Quotient - Adult 10 (AQ-10)

  The Autism Spectrum Quotient - Adult 10 is a brief self-report screening tool for adults without learning disabilities, designed to assess autistic traits. It consists of 10 items on social, attention, and cognitive preferences, scored to indicate possible need for further diagnostic evaluation.

  Year 2, Year 4

• World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0)

  The World Health Organization Disability Assessment Schedule 2.0 (12-item version) is a self-report instrument designed to assess disability and functioning associated with physical or mental health conditions, evaluating difficulties experienced over the past 30 days across key domains of daily functioning using a five-point response scale.

  Year 2, Year 4

• Mediterranean Diet Adherence Screener (MEDAS)

  The Mediterranean Diet Adherence Screener is a 14-item questionnaire assessing adherence to the Mediterranean diet.

  Year 3, Year 5

• Questionnaire on Caffeine, Natural Compounds, and Supplement Use

  The Questionnaire on Caffeine, Natural Compounds, and Supplement Use is an instrument that evaluates the frequency and patterns of consumption, providing an overview of participants' intake of stimulants and supplements.

  Year 3, Year 5

• Alcohol Consumption

  The Alcohol Consumption Questionnaire is an instrument that provides a concise evaluation of alcohol consumption habits and risky drinking behaviors in adult populations.

  Year 3, Year 5

• Generalized Anxiety Disorder 7-item scale (GAD-7)

  The Generalized Anxiety Disorder 7-item scale is a brief self-report tool used to screen for and assess the severity of generalized anxiety symptoms over the past 14 days.

  Year 3, Year 5

• University of California Los Angeles Loneliness Scale (UCLA v3)

  The University of California Los Angeles Loneliness Scale (v3) is a self-report questionnaire that assesses subjective feelings of loneliness and social isolation, capturing how often individuals feel connected to or disconnected from others.

  Year 3, Year 5

• Adult Attention-Deficit/Hyperactivity Disorder (ADHD) Self-Report Scale-V1.1 (ASRS-V1.1)

  The Adult Attention-Deficit/Hyperactivity Disorder (ADHD) Self-Report Scale-V1.1 Screener is a brief self-report questionnaire designed to identify symptoms of adult ADHD. It assesses difficulties with attention, organization, and hyperactivity/impulsivity over the past six months.

  Year 3, Year 5

• The Nordic Musculoskeletal Questionnaire (NMQ)

  The The Nordic Musculoskeletal Questionnaire is a tool used to identify musculoskeletal symptoms. It assesses the presence of pain, discomfort, or numbness in different body regions over the last 12 months, the last 7 days, and the impact on daily activities.

  Year 3, Year 5

• Roland-Morris Disability Questionnaire (RMDQ)

  The Roland-Morris Disability Questionnaire is a simple and widely used tool to assess how low back pain affects daily activities. It consists of 24 short statements that patients select according to their current condition, and the total score reflects the level of functional disability, with higher scores indicating greater limitation.

  Assessed at 2 years after the beginning of the study

• Adolescents and Adults Coordination Questionnaire (AAC-Q)

  The Adolescents and Adults Coordination Questionnaire is a self-report tool used to assess motor coordination difficulties in adolescents and adults. It evaluates problems related to fine and gross motor skills, daily activities, spatial orientation, organization and planning, and motor learning, helping to identify coordination difficulties that may impact everyday functioning.

  Assessed at 2 years after the beginning of the study and evaluated 2 years after

Secondary Outcomes (102)

• Postural control assessment - Mini-BESTest: Balance Evaluation Systems Test

  Year 2, Year 4

• Audiological Assessment (Otoacoustic Emissions and Impedanciometry)

  Baseline, Year 3

• Waldrop Physical Anomaly Scale

  Baseline

• Bioelectrical Impedance Analysis

  Baseline, Year 2, Year 3, Year 4, Year 5

• Blood pressure

  Baseline, Year 3

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The sample will consist of individuals aged 18 years or older who are enrolled at the Polytechnic Institute of Porto (P. Porto) from the 2025 academic year onwards, regardless of the level of study attended (CTeSP, bachelor's, master's, or doctoral programmes).

You may qualify if:

• years or older;
• Enrollment at the Polytechnic Institute of Porto (P. PORTO) from the 2025 academic year onward;
• Attendance in any cycle of study (CTeSP, bachelor's, master's, or doctoral programs);
• Willingness to participate voluntarily in the study;
• Ability to provide informed consent.

You may not qualify if:

• Lack of access to a computer or a mobile device with internet access.

Sponsors & Collaborators

• Polytechnic Institute of Porto: lead
• Center for Rehabilitation Research (CIR): collaborator
• Research Centre in Health and Environment (CISA): collaborator
• School of Health of Polytechnic Institute of Porto: collaborator
• Center for Translational Health and Medical Biotechnology Research (TBIO): collaborator

Study Sites (1)

E2S | P.PORTO School of Health of Polytechnic Institute of Porto

Porto, 4200-072, Portugal

RECRUITING

Related Links

• Project website

Central Study Contacts

Nuno B Rocha, PhD

CONTACT

+351 22 206 1000; bionorthealth@ess.ipp.pt

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Coordinating Professor with Habilitation, PhD

Study Record Dates

• First Submitted: April 13, 2026
• First Posted: September 22, 2026
• Study Start: October 1, 2025
• Primary Completion (Estimated): October 1, 2030
• Study Completion (Estimated): October 1, 2030
• Last Updated: September 22, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

PT (1)