NCT07830680

Brief Summary

The goal of this observational study is to evaluate the expression of miR-10a-5p in the blood in patients with sexual addiction or food addiction. The main question it aims to answer is : To determine whether adults patients with SA or FA exhibit a distinct blood miR-10a-5p expression profile compared with matched healthy controls. For all participants, one blood sample will be collected.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for all trials

Timeline
21mo left

Started Oct 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 15, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 21, 2026

Completed
10 days until next milestone

Study Start

First participant enrolled

October 1, 2026

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2028

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2028

Last Updated

September 24, 2026

Status Verified

September 1, 2026

Enrollment Period

1.5 years

First QC Date

September 15, 2026

Last Update Submit

September 21, 2026

Conditions

Food AddictionSexual Addiction

Outcome Measures

Primary Outcomes (1)

  • Blood miR-10a-5p expression

    The concentration of each miR-enriched fraction will be determined by spectrophotometric between patients with SA or FA and matched healthy controls.

    3 months

Secondary Outcomes (7)

  • Blood additional circulating miRs expression

    3 months

  • Clinical Characteristics

    3 months

  • Clinical Characteristics

    3 months

  • Clinical Characteristics

    3 months

  • Clinical Characteristics

    3 months

  • +2 more secondary outcomes

Study Arms (2)

Patients with addiction

Patients with food addiction (FA) or sexual addiction

Biological: blood sampling

Healthy controls

Healthy controls matched on sex and age to patients with food addiction or sexual addiction

Biological: blood sampling

Interventions

blood samplingBIOLOGICAL

One blood sample wiil be collected into a 10mL K2EDTA BD Vacutainer® tube

Healthy controlsPatients with addiction

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with food or sexual addiction, compared with age- and sex-matched healthy controls with no current addictive disorder.

You may qualify if:

  • For patients with FA:
  • Male and females ≥ 18 years old
  • Already in care or newly initiating care
  • Participating to EVALADD cohort
  • Current diagnosis of FA
  • Oral consent provided
  • Affiliated with French social security system or beneficiary from such system
  • For healthy controls matched to patients with FA:
  • Male and females ≥ 18 years old
  • Oral consent provided
  • Affiliated with French social security system or beneficiary from such system
  • For patients with SA:
  • Male ≥ 18 years old
  • Already in care or newly initiating care
  • Participating to EVALADD cohort
  • +7 more criteria

You may not qualify if:

  • For patients with FA:
  • Presence of a current diagnosis of SA
  • Presence of any current addictive disorder (substance \[except tobacco\] use disorders, gambling disorder, gaming disorder)
  • Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication)
  • Pregnancy or breastfeeding woman
  • Trusteeship or curatorship
  • Major cognitive impairment
  • Not fluent in French
  • For patients with SA:
  • Presence of a current diagnosis of FA
  • Presence of any current addictive disorder (substance \[except tobacco\] use disorders, gambling disorder, gaming disorder)
  • Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication)
  • Trusteeship or curatorship
  • Major cognitive impairment
  • Not fluent in French
  • +9 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nantes University Hospital

Nantes, France

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood will be collected into a 10mL K2EDTA BD Vacutainer® tube.

MeSH Terms

Conditions

Food AddictionCompulsive Sexual Behavior Disorder

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Behavior, AddictiveCompulsive BehaviorImpulsive BehaviorBehaviorFeeding and Eating DisordersMental DisordersSexual and Gender DisordersSexual Dysfunctions, Psychological

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Central Study Contacts

Pr Caroline Victorri-Vigneau

CONTACT

02.40.84.76.20marie.bronnec@chu-nantes.fr

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2026

First Posted

September 21, 2026

Study Start

October 1, 2026

Primary Completion (Estimated)

March 31, 2028

Study Completion (Estimated)

June 30, 2028

Last Updated

September 24, 2026

Record last verified: 2026-09

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)