NCT07828600

Brief Summary

The primary objective is to explore the differences in oral flora among healthy elderly individuals, those in a sub-healthy state, and those requiring long-term care. Furthermore, it will investigate whether different mental states, lifestyles, or dietary habits lead to variations in dominant oral flora. The study will also observe the degree of change in oral flora after intervention in oral hygiene care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
17

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 19, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2025

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2025

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

September 2, 2026

Completed
16 days until next milestone

First Posted

Study publicly available on registry

September 18, 2026

Completed
Last Updated

September 18, 2026

Status Verified

September 1, 2026

Enrollment Period

1 month

First QC Date

September 2, 2026

Last Update Submit

September 15, 2026

Conditions

Long-Term CareDementia

Outcome Measures

Primary Outcomes (4)

  • the gingival index

    mild, moderate and severe

    six weeks

  • calculus and tongue plaque index

    none, mild, moderate and severe

    six weeks

  • Residual root

    none, 0-4, more than 4

    six weeks

  • dental caries

    decay, missing

    six weeks

Study Arms (1)

oral moisturizer

EXPERIMENTAL

A thin, uniform layer of oral moisturizing gel (GC, Japan) was topically applied directly to the dorsal surface of the tongue and the surrounding oral mucosal surface.

Behavioral: oral moisturizer

Interventions

oral moisturizerBEHAVIORAL

A thin, uniform layer of oral moisturizing gel (GC, Japan) was topically applied directly to the dorsal surface of the tongue and the surrounding oral mucosal surface.

oral moisturizer

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • aged ≥65 years and having resided in the facility for ≥6 months.

You may not qualify if:

  • Individuals who were receiving systemic antimicrobial therapy were strictly excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Meiho university

Pingtung City, Taiwan, 912, Taiwan

Location

MeSH Terms

Conditions

Dementia

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assistant professor

Study Record Dates

First Submitted

September 2, 2026

First Posted

September 18, 2026

Study Start

June 19, 2025

Primary Completion

July 20, 2025

Study Completion

July 30, 2025

Last Updated

September 18, 2026

Record last verified: 2026-09

Data Sharing

IPD Sharing
Will not share

Locations

TW(1)