Assessment of Changes in Autonomy Through Analysis of Smartphone Usage Data in Patients With Alzheimer's Disease

NCT07826975 | Not Yet Recruiting

• 1 other identifier: 2025-A01157-42
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Alzheimer's disease is the leading cause of dementia worldwide. The first cognitive function to be affected is memory. As the disease progresses, other cognitive systems are affected, leading to a gradual loss of independence for the patient. This loss of independence is at the heart of the psychosocial and medico-economic challenges posed by Alzheimer's disease. Functional independence refers to the patient's ability to perform activities of daily living. The evolution of autonomy varies significantly from one individual to another, and a specific, personalized assessment is necessary in order to offer appropriate care and services. There is a link between patient autonomy and psycho-behavioral disorders. Early identification of loss of autonomy in connection with psycho-behavioral disorders would allow specific treatment to be put in place. The study hypothesis is that there is a link between changes in smartphone data and changes in the independence of patients with AD.

Conditions

Alzheimer Disease (AD)

Outcome Measures

Primary Outcomes (1)

• Comparison of changes in smartphone usage data and battery life collected at 0 and 18 months

  To measure the relationship between variations in smartphone usage data-represented as a single parameter created through a mathematical combination-and variations in the Amsterdam IADL questionnaire between 0 and 18 months.

  From enrollment to the end of participation at 18 months

Study Arms (1)

Alzheimer's patients

Other: Data collection; Other: Neuropsychological assesment; Other: Autonomy questionnaire

Interventions

Data collection OTHER

Collection of Android smartphone usage

Alzheimer's patients

Neuropsychological assesment OTHER

MMSE, FCSRT, FAB, TMT, verbal fluency test, Rey figure, BBEP, langage assesments and HAD scale

Alzheimer's patients

Autonomy questionnaire OTHER

IADL Amsterdam assessed by the caregiver

Alzheimer's patients

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients receiving routine care at a memory resource and research center for Alzheimer's disease who own an Android smartphone.

You may qualify if:

• Age ≥ 60 years
• Patient consulting on routine care at a memory resource and research center for Alzheimer's disease defined by cognitive memory complaints from the patient or their family and friends, evidence of impaired verbal episodic memory storage in FCSRT defined by a sum of FR values less than 17/48 and a sum of CR values less than 40/48 compared to the patient's age and socio-cultural level and no criteria on other neuropsychological tests, progressive decline over at least 6 months affecting independence, and if a brain MRI, a lumbar puncture, and/or an 18FDG PET scan were performed as part of the patient's routine care, the results must be consistent with a diagnosis of MA.
• Patient with a smartphone for their exclusive use that is compatible with the installation of the IMASMART application on Android
• No sensory impairment (vision or hearing impairment) that could compromise the use of a smartphone
• Absence of major anxiety-depressive disorder defined by a HAD score \> 16
• Patient an caregiver not objecting to participating in the study

You may not qualify if:

• Inability to perform the Mini-Mental State Examination or score \< 17
• Other neurodegenerative disorders
• Severe, unstable psychiatric disorders
• Terminal phase of a severe illness
• Other conditions that may compromise the use of a smartphone
• Patients with an iPhone
• MRI evidence of a lesion that may contribute to cognitive impairment (stroke, tumors, etc.)
• Refusal to install the application
• People residing in a residential care for senior or any other medical facility
• Individuals benefiting from enhanced protection, namely individuals deprived of their liberty by judicial or administrative decision, adults under legal protection, and finally, patients in emergency situations.

Sponsors & Collaborators

• Poitiers University Hospital: lead

MeSH Terms

Conditions

Alzheimer Disease

Interventions

Data Collection

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Céline ABONNEAU

  Poitiers University Hospital

  STUDY CHAIR

Central Study Contacts

Adrien JULIAN, MD

CONTACT

05.49.44.44.44; adrien.julian@chu-poitiers.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 18 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 10, 2026
• First Posted: September 18, 2026
• Study Start: September 1, 2026
• Primary Completion (Estimated): March 1, 2030
• Study Completion (Estimated): March 1, 2030
• Last Updated: September 18, 2026

Record last verified: 2026-08