NCT07826000

Brief Summary

This study aims to evaluate the effects of Tai Chi exercise on the physical performance of elderly individuals diagnosed with sarcopenia. Sarcopenia is characterized by a progressive loss of muscle mass and strength, which often leads to decreased physical function, mobility issues, and a higher risk of falls in older adults. Specifically, the research investigates the impact of an eight-week Tai Chi program on four key functional areas: handgrip strength measured by a dynamometer, balance evaluated through the 5-times Sit-to-Stand (5xSTS) test, mobility measured by the Timed Up and Go (TUG) test, and daily physical activity levels assessed via the Physical Activity Scale for the Elderly (PASE) questionnaire. The primary question this study seeks to answer is how Tai Chi exercise influences the physical performance of elderly patients with sarcopenia. Furthermore, it aims to determine whether practicing Tai Chi yields significant improvements in their handgrip strength, balance, mobility, and overall activity levels when compared to a control group participating in standard elderly gymnastics.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 24, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 18, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 18, 2026

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

September 12, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 17, 2026

Completed
Last Updated

September 17, 2026

Status Verified

September 1, 2026

Enrollment Period

3 months

First QC Date

September 12, 2026

Last Update Submit

September 12, 2026

Conditions

Keywords

sarcopeniatai chiphysical performance

Outcome Measures

Primary Outcomes (4)

  • Handgrip Strength

    This outcome measures upper body and global muscle strength using a CAMRY® handgrip dynamometer. Participants perform a maximum isometric contraction using their dominant hand, and the highest value from at least two trials is recorded. A higher value indicates greater muscle strength. The Asian Working Group for Sarcopenia (AWGS) 2019 recommends a diagnostic cutoff for low muscle strength of \<28.0 kg for men and \<18.0 kg for women

    Baseline (Week 0) and post-intervention (Week 8)

  • 5 Times Sit to Stand (5xSTS) Test

    This test assesses lower extremity muscle strength, balance, and postural control. It measures the time (in seconds) required for a participant to rise from a standard armless chair (17 inches high) to a full standing position and sit back down five times consecutively, with arms folded across the chest. A lower time indicates better physical performance and balance, with a normal value considered to be $\\le12$ seconds.

    Baseline (Week 0) and post-intervention (Week 8)

  • Timed Up and Go (TUG) Test

    This test measures functional mobility, dynamic balance, and the risk of falling. It evaluates the time (in seconds) it takes for a participant to stand up from a chair, walk a distance of 3 meters at a normal pace, turn around, walk back, and sit down again. A completion time of \<12 seconds indicates good mobility, while taking \>12 seconds indicates poor mobility and a higher risk of falls.

    Baseline (Week 0) and post-intervention (Week 8)

  • Physical Activity Scale for the Elderly (PASE) Score

    This outcome evaluates the self-reported physical activity levels of the participants over the previous 7 days. The PASE questionnaire calculates a total score based on the frequency, duration, and intensity of activities across three categories: leisure time, household chores, and work-related activities. Scores are categorized into less active (\<125) and active (\>= 125), with a higher score indicating a more active lifestyle.

    Baseline (Week 0) and post-intervention (Week 8)

Study Arms (2)

Tai Chi Exercise Group

EXPERIMENTAL

Elderly participants diagnosed with sarcopenia who are randomly assigned to participate in a supervised Tai Chi exercise program.

Behavioral: Tai Chi Exercise

Elderly Gymnastics (Senam Lansia) Group

ACTIVE COMPARATOR

Elderly participants diagnosed with sarcopenia who are randomly assigned to participate in a standard elderly gymnastics program

Behavioral: Elderly Gymnastics (Senam Lansia) Exercise

Interventions

The intervention group served as the experimental arm and participated in a Tai Chi exercise program. Each of their exercise sessions was led by a Tai Chi instructor and lasted for approximately 60 minutes, which consisted of a 10-minute warm-up, 30 minutes of core exercises, and a 10-minute cool-down. The participants in this group completed these training sessions three times a week over an eight-week period. After the eight-week period concluded, post-intervention data from both groups were collected and compared to their initial baseline measurements to evaluate which program yielded a more significant improvement in physical performance.

Tai Chi Exercise Group

The control group was established to compare the effectiveness of Tai Chi against a more conventional physical activity. Participants in this group engaged in a standard elderly gymnastics program (senam lansia). Their sessions were also guided by an instructor but had a shorter duration, lasting for approximately 30 minutes per session. Just like the intervention group, they performed these exercises three times a week for a total of eight weeks. After the eight-week period concluded, post-intervention data from both groups were collected and compared to their initial baseline measurements to evaluate which program yielded a more significant improvement in physical performance.

Elderly Gymnastics (Senam Lansia) Group

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged 60 years or older
  • Meets the diagnostic criteria for sarcopenia based on the Asian Working Group for Sarcopenia (AWGS).
  • Willing to participate in the study, capable of understanding the informed consent, and physically able to perform Tai Chi movements.
  • Must be a resident of Makassar.
  • Has either never participated in Tai Chi, or has previous experience with Tai Chi but stopped practicing for more than 4 weeks (ensuring they are not currently active practitioners).

You may not qualify if:

  • Cognitive impairment, indicated by a Mini-Mental State Examination (MMSE) score of 23 or lower.
  • Hearing and/or speech impairments that make communication difficult. Presence of severe chronic diseases, such as heart failure, end-stage chronic kidney disease, malignancy, or the use of a pacemaker.
  • Presence of edema (fluid retention/swelling).
  • Experiencing lower extremity (leg) pain with a Visual Analogue Scale (VAS) score of 5 or greater.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

GPIB Mount of Olives (Bukit Zaitun Church) Makassar

Makassar, South Sulawesi, 90126, Indonesia

Location

MeSH Terms

Conditions

Sarcopenia

Interventions

Aquatic TherapyExercise

Condition Hierarchy (Ancestors)

Muscular AtrophyNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesAtrophyPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsSigns and Symptoms

Intervention Hierarchy (Ancestors)

HydrotherapyPhysical Therapy ModalitiesTherapeuticsRehabilitationMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: The intervention group served as the experimental arm and participated in a Tai Chi exercise program. Each of their exercise sessions was led by a Tai Chi instructor and lasted for approximately 60 minutes, which consisted of a 10-minute warm-up, 30 minutes of core exercises, and a 10-minute cool-down. The participants in this group completed these training sessions three times a week over an eight-week period. On the other hand, the control group was established to compare the effectiveness of Tai Chi against a more conventional physical activity. Participants in this group engaged in a standard elderly gymnastics program (senam lansia). Their sessions were also guided by an instructor but had a shorter duration, lasting for approximately 30 minutes per session. Just like the intervention group, they performed these exercises three times a week for a total of eight weeks.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident of Physical Medicine and Rehabilitation Faculty of Medicine Hasanuddin University

Study Record Dates

First Submitted

September 12, 2026

First Posted

September 17, 2026

Study Start

January 24, 2026

Primary Completion

April 18, 2026

Study Completion

April 18, 2026

Last Updated

September 17, 2026

Record last verified: 2026-09

Data Sharing

IPD Sharing
Will not share

Locations