Electroencephalogram Changes Induced by Transcutaneous Electrical Acupoint Stimulation

NCT07819630 | Recruiting

• 1 other identifier: 2026-ke-49
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

A total of 90 subjects underwent abdominal surgery under general anesthesia at Chaoyang Hospital in Beijing. The subjects were divided into a percutaneous acupoint electrical stimulation group and a control group. The subjects were selected for TEAS stimulation at the Neiguan, Hegu, and Zusanli acupoints on both sides, and EEG data were collected using a 32 lead EEG cap test throughout the entire process. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded.

Conditions

Postoperative Pain

Outcome Measures

Primary Outcomes (1)

• Electroencephalogram analysis

  Changes in EEG in the experimental group with transcutaneous electrical acupoint stimulation compared to the baseline, as well as post - operative EEG changes in the experimental group and the control group.Including：node clustering coefficient，node efficiency，normalized mean clustering coefficient，normalized path length，modularity，small-world network

  Five - minute baseline EEG data with eyes closed during wakefulness；EEG data during pre - operative transcutaneous electrical acupoint stimulation；Immediate post - operative EEG data

Secondary Outcomes (1)

• Patients' VAS score

  24 hours after surgery

Study Arms (2)

Transcutaneous electrical acupoint stimulation group

EXPERIMENTAL

Group description: Participants in the reorganization will receive TEAS stimulation at bilateral Neiguan, Hegu, and Zusanli acupoints, and EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, changes in hemodynamic parameters (blood pressure, heart rate) and perioperative pain scores of the subjects will be recorded.

Device: Transcutaneous electrical acupoint stimulation

Control group

NO INTERVENTION

Attach electrodes to the same area but do not apply stimulation, while informing the patient that percutaneous acupoint electrical stimulation therapy has been performed

Interventions

Transcutaneous electrical acupoint stimulation DEVICE

Group description: Participants in this group will receive TEAS stimulation at the bilateral Neiguan, Hegu, and Zusanli acupoints 30 minutes before the start of the surgery, and their EEG data will be collected throughout the entire process using a 32 lead EEG cap test. During the experiment, the changes in hemodynamic parameters (blood pressure, heart rate) of the subjects during surgery will be recorded, as well as the perioperative pain scores of the subjects at 1 hour and 24 hours after surgery.

Transcutaneous electrical acupoint stimulation group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• Beijing Chao Yang Hospital: lead

Study Sites (1)

Affiliated Beijing Chaoyang Hospital of Capital Medical University, Beijing 100020

Beijing, China

RECRUITING

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Central Study Contacts

Wei

CONTACT

 +86 13810678936; changwei.wei@ccmu.edu.cn

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 6, 2026
• First Posted: September 15, 2026
• Study Start (Estimated): October 31, 2026
• Primary Completion (Estimated): February 28, 2027
• Study Completion (Estimated): March 30, 2027
• Last Updated: September 15, 2026

Record last verified: 2026-09

Locations

CN (1)