NCT07817992

Brief Summary

The aim of this study is to investigate the effect of virtual reality training on cervical mobility, proprioceptive accuracy and hand strength in patients with cervical radiculopathy. Forty patients of both sexes diagnosed with cervical radiculopathy will participate in this study. The participants' ages will be varied from 35 to 50 years, with a body mass index less than 30 kg/m². Patients will be randomly allocated to virtual reality and control groups. Both groups will receive a conventional physical therapy program in the form of electrotherapy, manual therapy, and strengthening exercises. The virtual reality group will receive virtual reality training in addition to the same physical therapy program. All participants will be assessed before and after treatment using the Joint Position Error by laser pointer for proprioceptive accuracy assessment; cervical ROM (CROM) for cervical mobility assessment; and hand dynamometer for hand grip strength. The treatment will be conducted three sessions per week for six weeks.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
8mo left

Started Dec 2026

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 9, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 14, 2026

Completed
3 months until next milestone

Study Start

First participant enrolled

December 1, 2026

Expected
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2027

19 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2027

Last Updated

September 14, 2026

Status Verified

August 1, 2026

Enrollment Period

7 months

First QC Date

September 9, 2026

Last Update Submit

September 9, 2026

Conditions

Cervical Radiculopathy

Keywords

cervical radiculopathyVirtual reality trainingPropioceptionCervical mobilityHand strength

Outcome Measures

Primary Outcomes (1)

  • Active cervical ROM (CROM)

    Cervical mobility will be assessed using an objective CROM goniometer. First, the patients will be asked to assume an upright sitting with the head in the neutral position. The CROM device will be placed firmly on the head and the the Velcro strap will be secured tightly and then calibrated. The sagittal, frontal, and horizontal gravity meters will be set to 0°. Then, each patient will be asked to perform active cervical ROM in the three planes as the following: flexion, extension, right and left rotation, and right and left side bending. The patients will be stabilized during all ROM assessments to prevent substitutions. All six ROMs will be recorded as degrees.

    From enrollment to the end of treatment at 6 weeks

Secondary Outcomes (2)

  • Joint Position Error for proprioceptive accuracy assessment

    From enrollment to the end of treatment at 6 weeks

  • Hand grip strength

    From enrollment to the end of treatment at 6 weeks

Study Arms (2)

Virtual Reality group

EXPERIMENTAL

Participants will receive 30 minutes of conventional physical therapy program in addition to 30 minutes of Virtual reality-based Training. The conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises. Virtual reality-based Training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality 3D glasses for 30 minutes per session, three sessions per week for 6 weeks.

Other: Virtual reality training using Shinecon Virtual Reality 3D GlassesOther: Conventional physical therapy program

Control group

ACTIVE COMPARATOR

Participants will receive 60 minutes of conventional physical therapy program. It will be the same as virtual reality group ( Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises).

Other: Conventional physical therapy program

Interventions

Virtual reality training using Shinecon Virtual Reality 3D GlassesOTHER

The virtual reality training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality for 30 minutes per session, three sessions per week for 6 weeks.

Virtual Reality group
Conventional physical therapy programOTHER

The conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS) (frequency of 50-100 Hz, a pulse duration between 50-200 µs, and an intensity adjusted to a comfortable, non-painful level), Ultrasound Therapy (frequency of 1 MHz, intensity of 0.5-1.0 W/cm², and a 50% duty cycle for pulsed ultrasound)., Manual Therapy ( Grade III and IV Cervical Mobilization, soft Tissue Manipulation in the form of Deep tissue massage and myofascial release techniques for the cervical and upper trapezius muscles, and Strengthening Exercises for cervical and upper limb muscles).

Control groupVirtual Reality group

Eligibility Criteria

Age35 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with unilateral cervical radiculopathy Patients aged 35 to 50 years. Both sexes The patient has experienced chronic neck pain for over six months. Neck pain intensity of 3 to 8 score by Visual Analog Scale. Positive findings in at least 3 out of 4 clinical assessments: Spurling's test, distraction test, upper limb tension test, and ipsilateral cervical rotation \< 60 degrees.
  • Body mass index less than 30 kg/m².

You may not qualify if:

  • Disorders of the temporomandibular joint.
  • Primary issues related to the shoulder or upper limb.
  • Neurological deficits, cognitive impairments (MOCA\< 25), or a history of cervical spine surgery.
  • Neck discomfort accompanied by dizziness or referred pain in both upper limbs.
  • Clinical instability, recent trauma, or vertebrobasilar insufficiency.
  • Structural irregularities of the spine (e.g., osteoporosis, ankylosing spondylitis, or rheumatoid arthritis).
  • Pregnant females

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Radiculopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System Diseases

Central Study Contacts

Marwa Mostafa

CONTACT

00201005661591marwamostsfa506@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer at Physical therapy for Neurology Department, Faculty of Physical Therapy, Cairo University

Study Record Dates

First Submitted

September 9, 2026

First Posted

September 14, 2026

Study Start (Estimated)

December 1, 2026

Primary Completion (Estimated)

July 1, 2027

Study Completion (Estimated)

July 20, 2027

Last Updated

September 14, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will not share