Yoga Based Cardiac Rehabilitation in Heart Failure Failure
Yoga-CaRe HF
Effectiveness of Yoga Based Cardiac Rehabilitation (Yoga-CaRe) in Heart Failure: A Randomized Controlled Clinical Trial
1 other identifier
interventional
3,500
1 country
16
Brief Summary
The clinical study compares the benefits of yoga based rehabilitation programme versus an educational package during recovery of patients with heart failure. Cardiac rehabilitation programmes help patients with cardiac illness to return as quickly as possible to full and productive life and to reduce the chances of further cardiac illness or death. We want to know whether our package of yoga classes can provide effective cardiac rehabilitation and how that compares with a package of educational classes. Both packages are especially designed by us to improve heart health
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Apr 2023
Longer than P75 for not_applicable
16 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 24, 2023
CompletedFirst Submitted
Initial submission to the registry
July 20, 2026
CompletedFirst Posted
Study publicly available on registry
September 14, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 30, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
November 30, 2026
September 14, 2026
October 1, 2025
3.6 years
July 20, 2026
September 7, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Major Adverse Cardiovascular event
Time to first cardiovascular event
Median follow-up of 1 year
Heart Failure Specific Quality of life
Change in the Minnesota Living with Heart Failure Questionnaire (MLHFQ) total score from baseline. The MLHFQ consists of 21 items, each scored from 0 (no impact) to 5 (very much impacted), with a total score ranging from 0 to 105. Lower scores indicate better health-related quality of life
3 months
Secondary Outcomes (8)
Six minute walk test
3 months
Generic Quality of life
3 months
Self-rated health (EQ-5D-5L)
3 months
Tobacco cessation
3 months
Self-reported Frailty
3 months
- +3 more secondary outcomes
Study Arms (2)
Yoga-CaRe group
EXPERIMENTALYoga based cardiac rehabilitation programme delivered as 20 sessions spread over three months and long term care and follow-up.
Enhanced standard care
ACTIVE COMPARATOREnhanced standard care comprising of health education delivered in 3 sessions spread over three months.
Interventions
A cardiac rehabilitation programme comprising of health education and yogic practices.
Health education on "Healthy Living with Heart Failure"
Eligibility Criteria
You may qualify if:
- Male and female patients above 18years
- Physician diagnosed heart failure patients with reduced ejection fraction based on ESC guidelines
- Patients should be NYHA class II/III
- Willing and able to attend the complete hospital-based CR programme on their own
You may not qualify if:
- Comorbid disease or behavioral or other limitations that interfere with performing Yoga training or prevent the completion of 1 y of exercise training
- Elective Cardiovascular procedure or hospitalization planned in the coming 3 months
- Currently pregnant or intend to become pregnant in the next year
- Heart failure secondary to significant correctable/reversible cause like primary valvular disease/ correctable congential heat disease
- Performance of exercise training/yoga at regular intervals (more than once per week) at a moderate-to-vigorous intensity at any time in the previous 6 week
- Participation in other clinical trials
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Centre for Chronic Disease Control, Indialead
- Indian Council of Medical Researchcollaborator
- Central Council for Research in Yoga & Naturopathycollaborator
- All India Institute of Medical Sciencescollaborator
- All India Institute of Medical Sciences, Bathindacollaborator
- All India Institute of Medical Sciences, Rishikeshcollaborator
- All India Institute of Medical Sciences, Jodhpurcollaborator
- Dayanand Medical College and Hospitalcollaborator
- KLES Prabhakar Kore Hospital Belagavicollaborator
- JSS Medical College Hospitalcollaborator
- SDM College of Medical Sciences & Hospitalcollaborator
- North Eastern Indira Gandhi Regional Institute of Health ans Medical Sciencescollaborator
- Sri Ramachandra Institute of Higher Education and Researchcollaborator
- Madras Medical Collegecollaborator
- Acharya Vinoba Bhave Rural Hospitalcollaborator
- Sri Jayadeva Institute of Cardiovascular Sciences and Researchcollaborator
Study Sites (16)
SDM College of Medical Sciences & Hospital
Dharwad, Karnataka, 580009, India
JSS Hospital
Mysore, Karnataka, 570004, India
North Eastern Indira Gandhi Regional Institute of Medical Sciences
Shillong, Meghālaya, 793018, India
All India Institute of Medical Sciences
New Delhi, National Capital Territory of Delhi, 110029, India
Dayanand Medical College and Hospital
Ludhiana, Punjab, 141001, India
All India Institute of Medical Sciences
Jodhpur, Rajasthan, 342005, India
Madras Medical College
Chennai, Tamil Nadu, 600003, India
Sri Ramchandra Institute of Higher Education and Research
Chennai, Tamil Nadu, 600116, India
All India Institute of Medical Sciences, Rishikesh
Rishikesh, Uttarakand, India
Sri Jayadeva Institute of Cardiovascular Sciences and Research
Bangalore, India
All India Institute of Medical Sciences, Bathinda
Bathinda, India
KLES Dr. Prabhakar Kore Charitable Hospital
Belagavi, India
Safdarjung Hospital
Delhi, India
Sir Ganga Ram Hospital
Delhi, India
Sri Jayadeva Institute of Cardiovascular Sciences and Research
Mysore, India
Acharya Vinobha Bhave Rural Hospital
Wardha, India
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Dorairaj Prabhakaran, MD DM (Cardiology)
Centre for Chronic Disease Control, New Delhi
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director
Study Record Dates
First Submitted
July 20, 2026
First Posted
September 14, 2026
Study Start
April 24, 2023
Primary Completion (Estimated)
November 30, 2026
Study Completion (Estimated)
November 30, 2026
Last Updated
September 14, 2026
Record last verified: 2025-10
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF
- Time Frame
- 12 months after completion of study follow-up
- Access Criteria
- Bonafide researchers will be provided access to data
We are preparing a IPD sharing plan