NCT07815093

Not Yet Recruiting

Multimodal Artificial Intelligence for Non-Invasive Colorect...

Xiuli Zuo Source

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Other study identifiers

Sponsor study identifier

KYLL-2026-06-037-1

Study Type

observational

Estimated enrollment

11,000

Locations

0 countries

Sites

N/A

Timeline

Study Start

October 1, 2026

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

April 1, 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

July 1, 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Brief Summary

The purpose of this study is to propose a non-invasive screening method by integrating holographic biological theory and artificial intelligence technology. A colorectal cancer risk assessment model will be constructed by analyzing multimodal data including facial features, tongue image characteristics and exhaled gas. The hypothesis of this study is that the model can attain both sensitivity and specificity of 80%.This study will enroll patients aged 18-80 years scheduled to undergo colonoscopy. All participants shall provide informed consent and sign the informed consent form. Patients will be excluded if they have severe cardiac, cerebral, pulmonary or renal dysfunction, or psychiatric disorders precluding colonoscopy, have a history of gastrointestinal surgery, or have taken bismuth agents or other staining medications. Based on estimates from existing literature, the training set will require tongue images, facial images, exhaled gas analysis results and colonoscopic diagnoses from 5000 patients, and the test set will require such data from 6000 patients.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: not yet recruiting
Estimated enrollment: 11,000 participants
Study completion date: July 1, 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Listed locations: 0 countries · 0 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
September 6, 2026
Actual (reported)
First Posted
September 11, 2026
Actual (reported)
Study Start
October 1, 2026
Estimated (date passed)
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Primary Completion
April 1, 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
July 1, 2028
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated: September 11, 2026
Status Verified: September 2026
Last Update Submitted: September 6, 2026

Conditions

Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

Presence of colonic polyps and colorectal cancer.
At the time of enrollment and colonoscopy examination

Interventions

Multimodal non-invasive detection for colorectal cancerOther

Collection of facial images, tongue images and exhaled gas data from participants. No therapeutic intervention is performed. The collected multimodal data will be used to build an artificial intelligence-based colorectal cancer risk assessment model.

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 80 Years

Sexall

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Participants aged 18-80 years who are scheduled to undergo colonoscopy. All participants provide informed consent. This study enrolls subjects preparing for colonoscopic examination to collect multimodal data for constructing an artificial intelligence-based colorectal cancer risk assessment model.

You may qualify if:

Patients aged 18-80 years scheduled to undergo colonoscopy.

Sponsors & Collaborators

Xiuli Zuo
Otherlead

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Study Design

Study Type: observational
Observational Model: OTHER
Time Perspective: OTHER
Target Duration: 1 Day
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: Professor, Chief Physician, Department of Gastroenterology

Study Record Dates

First Submitted

September 6, 2026

First Posted

September 11, 2026

Study Start

October 1, 2026

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Primary Completion

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All patients provide informed consent and sign the informed consent form.

You may not qualify if:

Patients with severe cardiac, cerebral, pulmonary or renal dysfunction, or psychiatric disorders that prevent colonoscopy;
Patients with a history of gastrointestinal surgery;
Patients taking bismuth agents or other staining medications.

Contact the study team to confirm eligibility.

April 1, 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

July 1, 2028

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated

September 11, 2026

Record last verified: 2026-09

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT07815093
Data provider: ClinicalTrials.gov
Source updated: 2026-09-11
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:31:21 UTC

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Design

Study Record Dates

You may not qualify if:

Source record