ADHD and Mental Effort

NCT07812714 | Not Yet Recruiting

• 2 other identifiers: APHP2601572026-A01213-48
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

ADHD is a common childhood disorder characterised by difficulties with attention and behaviour. Various cognitive characteristics are associated with ADHD, such as executive and motivational difficulties. Beyond these characteristics, our hypothesis is that children with ADHD may have specific strategies for allocating mental effort, influenced by motivational and metacognitive factors Our study assesses these dimensions using a behavioural task and a computational model in children with ADHD, both with and without treatment. It aims to identify individual cognitive profiles correlated with clinical characteristics. A better understanding of the cognitive mechanisms involved in ADHD would enable the development of personalised management of the disorder.

Conditions

ADHD

Keywords

ADHD; psychiatry; pediatry; mental effort

Outcome Measures

Primary Outcomes (1)

• group-level correlation between individual cognitive parameters (motivational and metacognitive) and individual clinical sub-scores for inattention and hyperactivity/impulsivity on the ADHDRS scale.

  To evaluate whether individual cognitive profiles derived from computational modeling explain a portion of the variability in individual clinical profiles in ADHD (inattention, hyperactivity/impulsivity).

  2 years

Secondary Outcomes (2)

• Mean within-participant difference between ADHD treatment conditions (ON vs OFF) in the computational-model-derived motivational parameter from the Memory and Stroop tasks

  2 years

• Mean within-participant difference between ADHD treatment conditions (ON vs OFF) in the computational-model-derived metacognitive parameter from the Memory and Stroop tasks

  2 years

Eligibility Criteria

• Age: 7 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Children aged between 7 years and 6 months and 18 years who have been diagnosed with ADHD and are being treated or hospitalised in the Child and Adolescent Psychiatry Department at Robert Debré Hospital, and who have not been diagnosed with ASD, an intellectual disability or a neurological condition.

You may qualify if:

• Patients diagnosed with ADHD according to the DSM-5 criteria.
• Receiving outpatient care or hospitalised within the Child and Adolescent
• Psychiatry Department at Robert Debré Hospital.
• Aged between 7 years and 6 months and under 18 years.
• Who understand, speak and can read French.

You may not qualify if:

• Presence of ASD or an intellectual disability.
• Presence of a neurological comorbidity, regardless of type.
• A person with parental authority who is under guardianship or conservatorship.
• A patient under a medical emergency authorization (AME).
• Objection expressed by at least one parent (regardless of the form: oral, written, or other).

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead
• Paris Brain Institute (ICM): collaborator

Study Sites (1)

Hôpital Robert Debré

Paris, 75019, France

Location

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Mental Disorders

Central Study Contacts

Eric ACQUAVIVA, MD

CONTACT

0140034092; eric.acquaviva@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 28, 2026
• First Posted: September 10, 2026
• Study Start: October 1, 2026
• Primary Completion (Estimated): October 1, 2028
• Study Completion (Estimated): October 1, 2028
• Last Updated: September 10, 2026

Record last verified: 2026-09

Locations

FR (1)