Adherence and Quality of Life Across Three Different Intermittent Fasting Protocols in Obese Working Women

NCT07804329 | Completed

• 2 other identifiers: UMREC_2245FP010-2023
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

In these recent years, Intermittent Fasting (IF) has become popular among the public and health fraternities not only because it produced evidence-based results as an alternative dietary approach in weight loss strategy, but also putative for its practical implementation to link with daily routine. IF is defined as a range of dietary regimens involving fasting for an extended time period (16-48hrs) with little to no energy intake on fast day. However, there are many types of IF regiments with different methodological approaches, and results are inconsistent and debatable. Therefore, it has raised a question on which IF regimen design will possibly maximise the health benefit. Thus, the aim of this study is to identify IF regimens that are most feasible and acceptable to working women. The purpose of this study was to examine which type of IF regiment is more feasible for weight loss intervention programmes by prescribing three different types of IF to participants

Conditions

Obese Adults

Keywords

Intermittent Fasting; Time Restricted Eating; Modified Alternate Day Fasting; Periodic Fasting; Adherence; Quality of Life

Outcome Measures

Primary Outcomes (1)

• Adherence Percentage

  Number of days adhered to daily energy requirement divided by total of intervention days. Adherence Percentage = (No. of days adhered to daily energy requirement/No. of intervention days)\*100

  Daly throughout 4 weeks of intervention. From Day 1 until Day 28

Secondary Outcomes (1)

• Anthropometry and Body Composition

  Pre and post-measurement. Measured at baseline (Day 1), and post-intervention (Day 28)

Other Outcomes (1)

• Health-related Quality of Life (HQoL)

  Measured at post-intervention only, at the end of 4 week of intervention, on day 28.

Study Arms (3)

MADF

EXPERIMENTAL

Different types of intermittent fasting protocol

Other: Adherence to the IF Protocol; Other: Quality of Life

TRE

EXPERIMENTAL

Type of IF

Other: Adherence to the IF Protocol; Other: Quality of Life

PF5:2

EXPERIMENTAL

Typr of IF

Other: Adherence to the IF Protocol; Other: Quality of Life

Interventions

Adherence to the IF Protocol OTHER

Adherence Percentage

Also known as: Adherence Percentage

MADF; PF5:2; TRE

Quality of Life OTHER

Survey of PCS and MCS Score

MADF; PF5:2; TRE

Eligibility Criteria

• Age: 25 Years - 50 Years
• Gender Eligibility Details: Working adult women aged 25-50 years were recruited through on-campus flyers and digital advertisements.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• a body mass index (BMI) of 27.5-32.4 kg/m² (obesity class I), low physical activity levels (\<150 minutes/week), and no prior participation in health or diet-related programs.

You may not qualify if:

• Women who were pregnant, had cardiovascular disease or a history of eating disorders were excluded

Sponsors & Collaborators

• Suriana Md Akir: lead

Study Sites (1)

Faculty of Sports and Exercise Science

Kuala Lumpur, 50603, Malaysia

Location

Related Publications (6)

• Varady KA, Cienfuegos S, Ezpeleta M, Gabel K. Clinical application of intermittent fasting for weight loss: progress and future directions. Nat Rev Endocrinol. 2022 May;18(5):309-321. doi: 10.1038/s41574-022-00638-x. Epub 2022 Feb 22.

  PMID: 35194176 BACKGROUND

• Allaf M, Elghazaly H, Mohamed OG, Fareen MFK, Zaman S, Salmasi AM, Tsilidis K, Dehghan A. Intermittent fasting for the prevention of cardiovascular disease. Cochrane Database Syst Rev. 2021 Jan 29;1(1):CD013496. doi: 10.1002/14651858.CD013496.pub2.

  PMID: 33512717 BACKGROUND

• Antoni R, Johnston KL, Collins AL, Robertson MD. Intermittent v. continuous energy restriction: differential effects on postprandial glucose and lipid metabolism following matched weight loss in overweight/obese participants. Br J Nutr. 2018 Mar;119(5):507-516. doi: 10.1017/S0007114517003890.

  PMID: 29508693 BACKGROUND

• Welton S, Minty R, O'Driscoll T, Willms H, Poirier D, Madden S, Kelly L. Intermittent fasting and weight loss: Systematic review. Can Fam Physician. 2020 Feb;66(2):117-125.

  PMID: 32060194 BACKGROUND

• Zang BY, He LX, Xue L. Intermittent Fasting: Potential Bridge of Obesity and Diabetes to Health? Nutrients. 2022 Feb 25;14(5):981. doi: 10.3390/nu14050981.

  PMID: 35267959 BACKGROUND

• 1. Lean MEJ. Management of obesity and overweight. Medicine (Baltimore). 2019;47(3):175-183. https://doi.org/10.1016/j.mpmed.2018.12.008

  BACKGROUND

Related Links

• National Health and Morbidity Survey (NHMS) 2023

MeSH Terms

Conditions

Intermittent Fasting

Interventions

Quality of Life

Condition Hierarchy (Ancestors)

Fasting; Feeding Behavior; Behavior

Intervention Hierarchy (Ancestors)

Health Status; Demography; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Officials

• Sareena Hanim Hamzah, Associate Proffesor

  Faculty of Sports and Exercise Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: PHD Student

Model Details: Randomised control trials. participant is randomised sigle blinded to one of the intermittent fasting protocols (TRE, MADF or PF5:2)

Study Record Dates

• First Submitted: August 12, 2026
• First Posted: September 4, 2026
• Study Start: April 1, 2023
• Primary Completion: June 1, 2023
• Study Completion: June 30, 2023
• Last Updated: September 4, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

MY (1)