Effects of Laughter Yoga in the Third Trimester

NCT07794371 | Enrolling By Invitation

• 1 other identifier: 2025 /37
• Study Type: interventional
• Target: 82
• Locations: 1 country
• Sites: 1

Brief Summary

Pregnancy is a physiological process during which a number of biological changes occur in a woman's body. This period represents an important turning point in the lives of women, whose reproductive capacity ensures the continuation of generations. While some women perceive pregnancy as a source of joy and happiness because of the anticipated arrival of a new family member, others may perceive it as a source of worry, anxious anticipation, and stress. In addition to physical and hormonal changes, expectant mothers experience numerous psychological and social changes during pregnancy. A woman's psychological state and experiences may influence the course of pregnancy, while pregnancy itself may also cause significant changes in her psychological state. Women who are unable to adequately adapt to these changes may experience various psychological problems due to pregnancy-related bodily changes and physical complaints, concerns about parenthood, changes in family and social roles, fear of childbirth, unwanted pregnancy and miscarriage, new challenges and needs arising from pregnancy, concerns and worries about the baby, parenting stress, low self-esteem, a persistent tendency toward negative thinking, lack of social support and social isolation, marital and partner-related problems, domestic violence, adverse life experiences, alcohol and tobacco use during pregnancy, chronic diseases, inadequate weight gain during pregnancy, exposure to sexual abuse, employment-related issues, and financial concerns. If these psychological problems arising during pregnancy are not resolved, emotional distress may continue to increase, potentially leading to stress and depression Symptoms of brain fog, such as forgetfulness and absent-mindedness, may occur once or twice during pregnancy or may persist throughout pregnancy. Brain fog may become more pronounced during periods of fatigue or irregular sleep, such as in the early or late stages of pregnancy. Studies conducted among pregnant women have shown that fluctuations in progesterone and estrogen during pregnancy may lead to impairments in attention, memory, and executive functioning because the brain is sensitive to changes in hormone levels. Laughter yoga (Laughter Therapy/Laughter Yoga), developed by Dr. Kataria, is a therapeutic method that combines yogic breathing techniques with laughter exercises. A systematic review reported that laughter yoga physiologically increases oxygenation, relaxes muscles, stimulates circulation and the immune system, increases endorphin release and thereby enhances the pain threshold and pain tolerance, strengthens mental functioning by reducing stress hormone levels, decreases depression and anxiety, improves sleep quality, and promotes psychological well-being by enhancing interpersonal relationships and social interaction. The literature highlights the positive physiological, psychological, and social effects of laughter on health. Although laughter yoga has increasingly been used in healthcare in recent years, positive outcomes have been reported across different age groups and health conditions. Laughter yoga performed with pregnant women has been reported to reduce the frequency of pregnancy-related symptoms and increase psychological well-being and prenatal attachment levels. However, no studies examining its effects on the outcomes addressed in the present study were identified in the literature. Therefore, this study aims to determine the effects of laughter yoga on perceived stress, psychosocial health, and brain fog among pregnant women in the third trimester. Keywords: laughter, pregnancy, stress, psychosocial health, brain fog

Conditions

Pregnancy; Psychosocial Health

Keywords

lLaughter,; pregnancy,; stress,; psychosocial health,; brain fog

Outcome Measures

Primary Outcomes (4)

• Descriptive Information Form:

  This form was developed by the researchers based on the relevant literature to assess the sociodemographic characteristics of the participants.

  Baseline and immediately after completion of the final laughter yoga session

• Perceived Stress Scale (PSS):

  The scale, developed by Cohen et al., consists of 14 items and was designed to assess the extent to which situations in an individual's life are perceived as stressful. Participants rate each item on a 5-point Likert-type scale ranging from "Never (0)" to "Very Often (4)." Seven positively worded items are reverse-scored. In the Turkish adaptation, reliability, and validity study of the Perceived Stress Scale conducted by Eskin et al., the Turkish PSS-14 demonstrated an internal consistency coefficient of 0.84 and a test-retest reliability coefficient of 0.87. The scale was concluded to be a valid and reliable instrument for assessing perceived stress.

  Baseline and immediately after completion of the final laughter yoga session

• The Antenatal Psychosocial Health Assessment Scale

  This scale was developed by Yıldız to assess psychosocial health during pregnancy. It consists of 46 items and six subscales: characteristics related to pregnancy and the spousal relationship, characteristics related to anxiety and stress, characteristics related to domestic violence, characteristics related to the need for psychosocial support, familial characteristics, and characteristics related to physical and psychosocial changes associated with pregnancy. The total score is divided by the number of items to obtain a mean score ranging from 1 to 5. Scores closer to 1 indicate greater psychosocial health problems during pregnancy, with a score of 1 representing very poor psychosocial health. The Cronbach's alpha coefficient of the scale was reported as 0.93.

  Baseline and immediately after completion of the final laughter yoga session

• Brain Fog Scale

  The scale consists of 30 items and three subscales. The total score ranges from 30 to 150. The Cognitive Symptoms subscale is scored between 17 and 85, the Physical Symptoms subscale between 8 and 40, and the Psychological Symptoms subscale between 5 and 25. Higher scores on the subscales and/or the overall scale indicate higher levels of brain fog.

  Baseline and immediately after completion of the final laughter yoga session

Study Arms (2)

1.laughter

EXPERIMENTAL

laughter therapy

Other: laughter therapy

2 CONTROL

NO INTERVENTION

Interventions

laughter therapy OTHER

Participants will receive a total of \*\*4-5 laughter therapy sessions\*\* during the study period.

1.laughter

Eligibility Criteria

• Age: 18 Years+
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being 18 years of age or older
• Having no communication barriers
• Applying for antenatal education during the study period
• Volunteering to participate in the study
• Being in the third trimester of pregnancy
• Having no condition that would prevent participation in laughter yoga sessions

You may not qualify if:

• Refusing to participate in the study
• Providing incomplete responses or failing to answer the questions in the questionnaire
• Having a high-risk pregnancy
• Having a multiple pregnancy (e.g., twins)

Sponsors & Collaborators

• Agri Ibrahim Cecen University: lead

Study Sites (1)

Ağrı İbrahim Çeçen University

Ağrı, Ağri, 04100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Mental Fatigue

Interventions

Laughter Therapy

Condition Hierarchy (Ancestors)

Fatigue; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asisst. prof

Study Record Dates

• First Submitted: August 25, 2026
• First Posted: August 31, 2026
• Study Start: November 30, 2025
• Primary Completion: March 30, 2026
• Study Completion (Estimated): November 30, 2026
• Last Updated: August 31, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)