Adductor Canal Block Versus Parasartorial Compartment Block for Pain Relief and Recovery After Arthroscopic Knee Surgery

NCT07790393 | Not Yet Recruiting

• 1 other identifier: CemreTez
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to compare adductor canal block and parasartorial compartment block for pain relief and functional recovery in adults undergoing elective arthroscopic knee surgery. The main questions it aims to answer are: Which block provides better pain relief at rest and during movement 24 hours after surgery? How do the two blocks compare in opioid use, muscle strength, knee movement, early walking, side effects, and patient satisfaction? Researchers will compare participants who receive an adductor canal block with those who receive a parasartorial compartment block to determine whether one technique provides better pain relief and functional recovery while preserving muscle strength. Participants will: Be randomly assigned to receive either an ultrasound-guided adductor canal block or an ultrasound-guided parasartorial compartment block Have their pain at rest and during knee movement assessed for 48 hours after surgery Have their opioid use, quadriceps muscle strength, knee movement, walking ability, side effects, and satisfaction evaluated after surgery

Conditions

Postoperative Pain After Arthroscopic Knee Surgery

Keywords

Adductor Canal Block; Postoperative Pain; Parasartorial Compartment Block

Outcome Measures

Primary Outcomes (1)

• Pain at Rest 24 Hours After Surgery

  Pain intensity at rest will be assessed using the Numeric Rating Scale, ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Lower scores indicate less pain.

  24 hours

Study Arms (2)

Adductor Canal Block

ACTIVE COMPARATOR

Drug: Meperidine

Parasartorial Compartment Block

ACTIVE COMPARATOR

Drug: Meperidine

Interventions

Meperidine DRUG

If the patient's NRS is 4 or more, 0.5 mg/kg meperidine will be given

Adductor Canal Block; Parasartorial Compartment Block

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Scheduled for elective unilateral primary arthroscopic knee surgery

You may not qualify if:

• Revision or bilateral arthroscopic knee surgery
• Surgery performed for trauma or an emergency indication
• Contraindications to regional nerve block, including infection at the injection site, coagulopathy, or inappropriate anticoagulant use
• Allergy to amide-type local anesthetics
• Pre-existing peripheral neuropathy or motor deficit in the limb to be operated on
• Dysfunction of the contralateral limb severe enough to interfere with functional assessments
• Chronic opioid use
• Severe cognitive impairment
• Pregnancy or lactation

Sponsors & Collaborators

• Istanbul Medipol University Hospital: lead

Study Sites (1)

Medipol Mega Hastaneler Kompleksi

Istanbul, Bagcilar, 34214, Turkey (Türkiye)

Location

Related Publications (4)

• Gungor H, Atalay YO. Para-sartorial compartments (Pasc) block for knee surgeries: a report of five cases. Minerva Anestesiol. 2023 Jun;89(6):606-608. doi: 10.23736/S0375-9393.23.17124-0. Epub 2023 Feb 8. No abstract available.

  PMID: 36752608 RESULT

• Pascarella G, Costa F, Del Buono R, Strumia A, Cataldo R, Agro F, Carassiti M. The para-sartorial compartments (PASC) block: a new approach to the femoral triangle block for complete analgesia of the anterior knee. Anaesth Rep. 2022 May 5;10(1):e12165. doi: 10.1002/anr3.12165. eCollection 2022 Jan-Jun. No abstract available.

  PMID: 35547556 RESULT

• Espelund M, Grevstad U, Jaeger P, Holmich P, Kjeldsen L, Mathiesen O, Dahl JB. Adductor canal blockade for moderate to severe pain after arthroscopic knee surgery: a randomized controlled trial. Acta Anaesthesiol Scand. 2014 Nov;58(10):1220-7. doi: 10.1111/aas.12407.

  PMID: 25307707 RESULT

• Chen B, Tan M, Li Q, Wang S, Chen D, Zhao M, Cao J. Application of ultrasound-guided single femoral triangle and adductor canal block in arthroscopic knee surgery: a prospective, double-blind, randomized clinical study. BMC Anesthesiol. 2024 May 23;24(1):182. doi: 10.1186/s12871-024-02555-0.

  PMID: 38783177 RESULT

MeSH Terms

Conditions

Pain, Postoperative

Interventions

Meperidine

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Isonipecotic Acids; Acids, Heterocyclic; Heterocyclic Compounds; Piperidines; Heterocyclic Compounds, 1-Ring

Central Study Contacts

Fatma P Ucar, MD

CONTACT

+905377697281; fpinarucar@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: M.D.

Study Record Dates

• First Submitted: August 25, 2026
• First Posted: August 27, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): June 1, 2027
• Last Updated: August 27, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)