NCT07782606

Brief Summary

This study investigated the acute and short-term effects of neuroathletic training (NAT)-integrated resistance training compared with conventional resistance training on physical and neuromuscular performance in collegiate athletes. Fifty-eight collegiate athletes completed two experimental resistance training sessions separated by one week. The conventional resistance training condition was performed first, followed one week later by a NAT-integrated resistance training condition. Both sessions included the same lower-extremity resistance exercises, training volume, intensity, exercise order, and rest intervals. During the NAT-integrated condition, visual, vestibular, gaze-stabilization, and proprioceptive drills were incorporated before selected resistance sets and during rest intervals. Sprint acceleration, bilateral and unilateral jump performance, eccentric hamstring strength, bilateral hamstring maximum difference, and sit-and-reach flexibility were assessed before training, immediately after training, 15 minutes after training, and 30 minutes after training.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
58

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 10, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 10, 2026

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 10, 2026

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 20, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 24, 2026

Completed
Last Updated

August 25, 2026

Status Verified

August 1, 2026

Enrollment Period

1 month

First QC Date

August 20, 2026

Last Update Submit

August 24, 2026

Conditions

Keywords

Neuroathletic trainingNeural primingCollegiate athletesEccentric hamstring strengthJump performanceVisual trainingVestibular stimulationH-Bord

Outcome Measures

Primary Outcomes (3)

  • Bilateral Hamstring Maximum Difference (MD)

    Maximum between-limb difference in eccentric hamstring strength. MD was calculated as: MD (%) = \|Right limb value - Left limb value\| / higher limb value × 100 Lower values indicate greater bilateral symmetry.

    Baseline, immediately post-training, 15 minutes post-training, and 30 minutes post-training during each experimental session.

  • Eccentric Hamstring Strength

    Eccentric hamstring strength was assessed using the IVMES H-Bord during the Nordic hamstring exercise. Peak eccentric force was recorded separately for the left and right limbs (Max Left and Max Right), together with device-derived left- and right-side strength outputs (T Left and T Right).

    Baseline, immediately post-training, 15 minutes post-training, and 30 minutes post-training during each of the two experimental sessions separated by one week.

  • Sit-and-Reach Flexibility

    Hamstring-related posterior chain flexibility assessed using the standard sit-and-reach test. Distance was recorded in centimeters, with higher values representing greater flexibility.

    Baseline, immediately post-training, 15 minutes post-training, and 30 minutes post-training during each experimental session.

Secondary Outcomes (4)

  • 5-Meter Sprint Acceleration

    Baseline, immediately post-training, 15 minutes post-training, and 30 minutes post-training during each experimental session.

  • Bilateral Jump Performance

    Baseline, immediately post-training, 15 minutes post-training, and 30 minutes post-training during each experimental session.

  • Right-Leg Unilateral Jump

    Baseline, immediately post-training, 15 minutes post-training, and 30 minutes post-training during each experimental session.

  • Left-Leg Unilateral Jump

    Baseline, immediately post-training, 15 minutes post-training, and 30 minutes post-training during each experimental session.

Study Arms (1)

Fixed-Order Conventional and NAT-Integrated Resistance Training

EXPERIMENTAL

All enrolled athletes completed two experimental sessions separated by one week. During the first session, participants completed conventional lower-extremity resistance training. During the second session, participants completed the same resistance training program with additional neuroathletic visual, vestibular, gaze-stabilization, and proprioceptive drills performed before selected sets and during rest intervals.

Other: Conventional Lower-Extremity Resistance TrainingOther: Neuroathletic Training-Integrated Resistance Training

Interventions

Participants completed a standardized lower-extremity resistance training session consisting of six exercises: leg press, Romanian deadlift, leg extension, seated leg curl, dumbbell step-up, and Copenhagen exercise. Leg press: 4 sets of 8-10 repetitions at approximately RPE 7-8, with 90 seconds rest. Romanian deadlift: 4 sets of 6-8 repetitions with a controlled 4-second eccentric phase and 90 seconds rest. Leg extension: 4 sets of 8-12 repetitions with an explosive concentric phase and 75-90 seconds rest. Seated leg curl: 4 sets of 8-10 repetitions with a 4-5-second eccentric phase and 90 seconds rest. Dumbbell step-up: 3 sets of 6-8 repetitions per leg with 90 seconds rest. Copenhagen exercise: 3 sets of 20-30 seconds per side with 60-90 seconds rest. Rest intervals consisted of passive rest only. No visual, vestibular, proprioceptive, gaze-stabilization, unilateral eye-occlusion, saccular, or utricular drills were performed.

Fixed-Order Conventional and NAT-Integrated Resistance Training

Participants completed the same lower-extremity resistance training protocol used in the conventional condition. The NAT-integrated condition additionally included a 6-8-minute pre-session neuroathletic activation block and brief neuroathletic primers before selected resistance sets and during rest intervals. The neuroathletic components included binocular convergence-divergence exercises, monocular convergence-divergence with unilateral eye occlusion, vertical vestibular/saccular stimulation, horizontal or linear vestibular stimulation, gaze stabilization, head-position variation, and proprioceptive awareness tasks. The purpose of these drills was to provide acute neural priming through visual, vestibular, oculomotor, proprioceptive, and sensorimotor stimulation while maintaining the same resistance training volume and intensity as the conventional condition.

Fixed-Order Conventional and NAT-Integrated Resistance Training

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Were collegiate athletes participating in organized sport training.
  • Had participated in regular sport-specific training for at least one year.
  • Had previous experience with lower-extremity resistance training.
  • Had previous experience with the exercises used in the study, including leg press, Romanian deadlift, leg extension, seated leg curl, dumbbell step-up, and Copenhagen exercise.
  • Were familiar with maximal or near-maximal sprinting, jumping, and lower-limb strength testing.
  • Were able to complete 5-meter sprint testing, bilateral and unilateral jump testing, Nordic hamstring testing, sit-and-reach flexibility testing, and the resistance training protocols.
  • Were able to perform maximal or near-maximal lower-limb tasks without pain or movement restriction.
  • Agreed to attend both experimental sessions and all measurement time points.

You may not qualify if:

  • Had an acute lower-extremity musculoskeletal injury during the previous three months.
  • Had a hamstring strain, quadriceps strain, groin injury, ankle sprain, knee injury, hip injury, or low back pain limiting sport participation during the previous three months.
  • Had undergone lower-extremity surgery during the previous 12 months.
  • Experienced current pain during sprinting, jumping, Nordic hamstring testing, flexibility testing, or resistance exercise.
  • Had a neurological disorder.
  • Had diagnosed vestibular dysfunction.
  • Had recurrent vertigo or unexplained dizziness.
  • Had severe motion sensitivity.
  • Had a balance disturbance.
  • Had uncorrected visual impairment.
  • Had diplopia or severe visual tracking difficulties.
  • Had any condition preventing safe completion of eye-occlusion or gaze-stabilization exercises.
  • Had experienced concussion within the previous six months.
  • Had persistent post-concussion symptoms.
  • Had cardiovascular, respiratory, metabolic, or systemic disease limiting high-intensity exercise.
  • +4 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kütahya Dumlupınar University

Kütahya, 43100, Turkey (Türkiye)

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Model Details: Non-Randomized
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 20, 2026

First Posted

August 24, 2026

Study Start

March 10, 2026

Primary Completion

April 10, 2026

Study Completion

June 10, 2026

Last Updated

August 25, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will share

De-identified individual participant data will be available from the corresponding author upon reasonable request, subject to applicable ethical and institutional requirements.

Locations