Comparing Vitamin D Results and Acceptability of Sampling Obtained From Dried Blood Spot, Tasso+ Capillary Sampling, and Venous Blood.

NCT07782528 | Not Yet Recruiting

• 1 other identifier: 2026LAB148
• Study Type: interventional
• Target: 35
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study will evaluate the performance and acceptability of different sampling methods for measuring vitamin D, specifically 25-hydroxyvitamin D₂ and 25-hydroxyvitamin D₃.

Conditions

Vitamin D

Keywords

Vitamin D Tasso

Outcome Measures

Primary Outcomes (1)

• Agreement between Tasso+ capillary serum and venous serum 25(OH)D

  Continuous 25(OH)D₂ and 25(OH)D₃ concentrations (nmol/L)

  From Study start date for up to 12 months

Secondary Outcomes (14)

• User acceptability

  From Study start date for up to 12 months

• User acceptability

  From study start date to 12 months

• User acceptability

  From Study start date for up to 12 months

• User acceptability

  From Study start date for up to 12 months

• User acceptability

  From Study start date for up to 12 months

Study Arms (1)

Vitamin D sampling

EXPERIMENTAL

Staff members having Vit D sampling using blood spot, venous samples, and sample collected using the device

Device: Vit D Tasso+

Interventions

Vit D Tasso+ DEVICE

Blood collected using Tasso device

Vitamin D sampling

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18 years or older.
• Current healthcare staff or staff volunteers.
• Already consented to use the routine dried blood spot (DBS) vitamin D service.
• Able and willing to provide all three sample types- routine DBS finger-prick sample, a Tasso+ upper-arm self-collected capillary sample, and a venous blood sample taken by a trained Trust phlebotomist.
• Able to give informed consent.
• Able to complete a short questionnaire in English.

You may not qualify if:

• Participants will not be able to take part if any of the following apply:
• Under 18 years of age
• Not a member of staff or staff volunteer
• Known difficulty with blood sampling, such as a history of fainting, severe needle phobia, or conditions that make venepuncture unsafe.
• Skin conditions or injuries on the upper arm that would prevent safe use of the Tasso+ device.
• Bleeding disorders or current use of anticoagulant medication that would make capillary or venous sampling unsafe.
• Inability to give informed consent, including difficulty understanding the study information.
• Inability to complete the short questionnaire in English, as this is needed to assess user experience.

Sponsors & Collaborators

• The Royal Wolverhampton Hospitals NHS Trust: lead

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 14, 2026
• First Posted: August 24, 2026
• Study Start (Estimated): January 1, 2027
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: August 24, 2026

Record last verified: 2026-08