Perceptions of Leadership in Quality Culture for Infection Prevention Among Intensive Care Nurses and Unit-Based Assessment of Antimicrobial Resistance Indicators in Intensive Care Units

NCT07782372 | Not Yet Recruiting

• 1 other identifier: Quality Culture (LCQ-IP)
• Study Type: observational
• Target: 127
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to examine intensive care nurses' perceptions of leadership in quality culture for infection prevention and to investigate antimicrobial resistance indicators at the intensive care unit level. Healthcare-associated infections (HAIs) remain a major global patient safety problem and are associated with prolonged hospital stays, increased healthcare costs, and higher mortality. The increasing prevalence of antimicrobial resistance (AMR) further complicates infection prevention and patient care. Intensive care units are particularly vulnerable to healthcare-associated infections and antimicrobial resistance because of the high frequency of invasive procedures, the vulnerability of critically ill patients, and the extensive use of broad-spectrum antibiotics. Nurses play a central role in infection prevention and antimicrobial stewardship because they are continuously involved in patient care. However, previous studies have reported a gap between nurses' knowledge of infection prevention and adherence to recommended practices in clinical settings. Organizational culture and leadership may contribute to this gap. Most previous studies have focused on healthcare professionals' self-reported perceptions of infection prevention. However, limited evidence is available regarding the relationship between nurses' perceptions of leadership and quality culture and objective antimicrobial resistance indicators at the intensive care unit level. Therefore, this study will assess nurses' perceptions using the Leadership in Quality Culture for Infection Prevention (LCQ-IP) instrument and examine their relationship with retrospective microbiological data from the participating intensive care units, including antimicrobial resistance rates and resistance profiles. The findings may provide evidence on the role of organizational leadership and quality culture in infection prevention and antimicrobial resistance management in intensive care settings.

Conditions

Healthcare-associated Infections; Quality Culture and Leadership in Intensive Care; Infection Prevention and Control

Keywords

Intensive care nurses; Infection prevention and control; Quality culture; Leadership

Outcome Measures

Primary Outcomes (1)

• Leadership in Quality Culture for Infection Prevention (LCQ-IP) score among intensive care nurses

  Leadership for a culture of quality in infection prevention will be assessed using the Turkish version of the Leading a Culture of Quality for Infection Prevention Scale. The scale consists of 16 items rated on a 5-point Likert scale. Total scores range from 16 to 80, with higher scores indicating a more positive perception of leadership for a culture of quality in infection prevention.

  Baseline

Secondary Outcomes (1)

• Antimicrobial Susceptibility Profiles of Bacterial Isolates from Intensive Care Units

  The 1-year period preceding study enrollment

Study Arms (2)

Bursa

Intensive Care Nurses and Intensive Care Units in Bursa

Iğdır

Intensive Care Nurses and Intensive Care Units in Iğdır

Eligibility Criteria

• Age: Up to 125 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of nurses actively working in intensive care units in participating hospitals in Bursa and Iğdır, Türkiye. Eligible participants will be nurses who have been actively working in an intensive care unit for at least 1 year and who voluntarily agree to participate in the study. Student nurses, nursing interns, nurses working temporarily or on a rotational basis in intensive care units, and nurses with less than 1 year of intensive care experience will be excluded.

You may qualify if:

• Nurses who have been actively working in an intensive care unit for at least 1 year.
• Nurses who voluntarily agree to participate in the study.

You may not qualify if:

• Student nurses or nursing interns.
• Nurses working temporarily or on a rotational basis in the intensive care unit.
• Nurses who have been actively working in an intensive care unit for at least 1 year.

Sponsors & Collaborators

• Yeliz Sapulu Alakan: lead

MeSH Terms

Conditions

Cross Infection

Condition Hierarchy (Ancestors)

Infections; Iatrogenic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Yeliz Alakan, PhD lecturer

CONTACT

90 505 850 0222; yelizsapulu@uludag.edu.tr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: August 17, 2026
• First Posted: August 24, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): December 30, 2026
• Last Updated: August 24, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share