NCT07780851

Brief Summary

The goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses for one month is related to change in eye length (axial length). The main questions it aims to answer are:

  • Attend three study visits at the Singapore Polytechnic Optometry Centre.
  • Wear the assigned study spectacles while performing near-vision tasks.
  • Have video recordings of their face collected, to evaluate eye and head movements, during the near-vision tasks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2025

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 2, 2025

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 9, 2026

Completed
14 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 23, 2026

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 18, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 24, 2026

Completed
Last Updated

August 24, 2026

Status Verified

June 1, 2026

Enrollment Period

11 months

First QC Date

August 18, 2026

Last Update Submit

August 21, 2026

Conditions

Myopia

Keywords

eye gazelens gazehead movementmyopia control

Outcome Measures

Primary Outcomes (2)

  • Change in eye gaze position

    Eye gaze positions are derived from post-processed video recordings of participants performing near-vision tasks while wearing the study spectacles.

    Visit 1 (Baseline), Visit 2 (1-2 weeks), Visit 3 (1-month)

  • Change in axial length

    Visit 2 (Baseline), Visit 3 (1-month)

Other Outcomes (2)

  • Change in head movement pattens

    Visit 1 (Baseline), Visit 2 (1-2 weeks), Visit 3 (1-month)

  • Change in scores of the Pediatric Refractive Error Profile (PREP) version 2 questionnaire

    Visit 2 (Baseline), Visit 3 (1-month)

Study Arms (1)

Sequential Lens Evaluation

EXPERIMENTAL

Single-arm, within-subject design; Each participant received both Single Vision Lens (SVL) and Myopia Control Lens (MCL) spectacles.

Device: Single Vision Lens (SVL)Device: Myopia Control Lens (MCL)

Interventions

Single Vision Lens (SVL)DEVICE

Standard, commercially available single vision spectacle lenses worn on-site during near vision task assessment at Visit 2 and Visit 3.

Sequential Lens Evaluation
Myopia Control Lens (MCL)DEVICE

Commercially available Stellest® spectacle lenses worn on-site during near vision task assessment at Visit 2 and Visit 3, and worn continuously for approximately 1 month between Visit 2 and Visit 3.

Sequential Lens Evaluation

Eligibility Criteria

Age8 Years - 15 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Between 8 and 15 years of age
  • No amblyopia
  • No tropia
  • No known/reported ocular pathology
  • Myopes with spherical equivalent refraction of -0.50 D to -6.00 D
  • Astigmatism of less than -4.00 D
  • Anisometropia of less than -1.50D
  • Best corrected monocular VA better than 0.10 logMAR in both eyes
  • Able to follow the protocol
  • Wearing habitual correction

You may not qualify if:

  • Currently or previously on any myopia control interventions (I.e., Myopia control spectacle lenses, myopia control contact lenses, orthokeratology lenses or atropine, etc.)
  • Myopes who do not have a pair of habitual glasses

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Singapore Polytechnic Optometry Centre (SPOC)

Singapore, Singapore, 139651, Singapore

Location

Related Publications (3)

  • Gao Y, Lim EW, Yang A, Drobe B, Bullimore MA. The impact of spectacle lenses for myopia control on visual functions. Ophthalmic Physiol Opt. 2021 Nov;41(6):1320-1331. doi: 10.1111/opo.12878. Epub 2021 Sep 16.

    PMID: 34529275BACKGROUND

  • Li X, Ding C, Li Y, Lim EW, Gao Y, Fermigier B, Yang A, Chen H, Bao J. Influence of Lenslet Configuration on Short-Term Visual Performance in Myopia Control Spectacle Lenses. Front Neurosci. 2021 May 25;15:667329. doi: 10.3389/fnins.2021.667329. eCollection 2021.

    PMID: 34113234BACKGROUND

  • Bao J, Huang Y, Li X, Yang A, Zhou F, Wu J, Wang C, Li Y, Lim EW, Spiegel DP, Drobe B, Chen H. Spectacle Lenses With Aspherical Lenslets for Myopia Control vs Single-Vision Spectacle Lenses: A Randomized Clinical Trial. JAMA Ophthalmol. 2022 May 1;140(5):472-478. doi: 10.1001/jamaophthalmol.2022.0401.

    PMID: 35357402BACKGROUND

Related Links

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Study Officials

  • Danny Sim

    Singapore Polytechnic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 18, 2026

First Posted

August 24, 2026

Study Start

April 2, 2025

Primary Completion

March 9, 2026

Study Completion

March 23, 2026

Last Updated

August 24, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations

SG(1)