NCT07775053

Brief Summary

In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy. The patients will be divided into two groups one group will receive modified pectoral nerve block with local anesthetic ropivacaine combined with tramadol and other group will receive pectoral nerve block with ropivacaine only

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P25-P50 for not_applicable postoperative-pain

Timeline
12mo left

Started Jan 2026

Typical duration for not_applicable postoperative-pain

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress40%
Jan 2026Aug 2027

Study Start

First participant enrolled

January 22, 2026

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

August 15, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 20, 2026

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2027

Last Updated

August 24, 2026

Status Verified

August 1, 2026

Enrollment Period

1.5 years

First QC Date

August 15, 2026

Last Update Submit

August 20, 2026

Conditions

Postoperative Pain

Outcome Measures

Primary Outcomes (1)

  • Postoperative Pain with visual analogue scale

    Post operatively pain will be accessed by visual analogue scale . Visual analogue scale (VAS) scale has score from 0 to 10 where 0 score indicate no or minimal pain and score of 10 indicate worst possible pain.

    24 hours postoperatively

Study Arms (2)

Ropivacaine with tramadol

OTHER
Procedure: Pectoral Nerve Block

Ropivacaine Alone

OTHER
Procedure: Pectoral Nerve Block

Interventions

Pectoral Nerve BlockPROCEDURE

One group will receive ropivacaine with tramadol in modified pectoral nerve block

Ropivacaine with tramadol

Eligibility Criteria

Age20 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Female Patients aged 20-70 years
  • Patients scheduled for elective unilateral modified radical mastectomy
  • Patients with ASAI andII physical status.

You may not qualify if:

  • Patients on anticoagulant therapy.
  • Patients with a BMI≥35 kg/m3.
  • Patients with a history of allergy to local anesthetics.
  • Patients with significant neurological or psychiatric disorders.
  • Pregnant patients.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dr Faisal Masood teaching Hospital Sargodha

Sargodha, Punjab Province, 40100, Pakistan

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 15, 2026

First Posted

August 20, 2026

Study Start

January 22, 2026

Primary Completion (Estimated)

August 1, 2027

Study Completion (Estimated)

August 1, 2027

Last Updated

August 24, 2026

Record last verified: 2026-08

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)