Ultrasound Biomicroscopic Assessment of Intraocular Lens Tilt and Decenteration After Phacoemulsification

NCT07769944 | Recruiting

• 1 other identifier: Soh-Med-26-6-6MS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to assess intraocular lens (IOL) tilt and decenteration by means of ultrasound biomicroscopy after phacoemulsification.

Conditions

Ultrasound Biomicroscopy; Intraocular Lens; Tilt; Decenteration; Phacoemulsification

Outcome Measures

Primary Outcomes (1)

• Measurement of intraocular lens tilt

  Measurement of intraocular lens (IOL) tilt. The intraocular lens (IOL) position was measured as the Anterior Chamber Depth (ACD), defined as the distance between the anterior border of the hyperreflective line marking the central posterior corneal surface and the anterior IOL optic surface at the centre of the pupillary space.

  Six months after surgery

Secondary Outcomes (1)

• Measurement of intraocular lens decenteration

  Six months after surgery

Study Arms (2)

Group 1

Patients with implanted hydrophilic intraocular lens (IOL).

Device: Ultrasound biomicroscopy

Group 2

Patients with implanted hydrophobic intraocular lens (IOL).

Device: Ultrasound biomicroscopy

Interventions

Ultrasound biomicroscopy DEVICE

Scanning is conducted with the non-dilated eye in a central position and the patient in the supine position. A drop of a topical anesthetic agent (benoxinate hydrochloride) is applied to both eyes.

Group 1; Group 2

Eligibility Criteria

• Age: Up to 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

A prospective, observational, hospital-based study which will be conducted in the Department of Ophthalmology, Sohag University Hospital, Egypt.

You may qualify if:

• Both sexes.
• Patients with senile cataract prepared for phacoemulsification and IOL implantation.

You may not qualify if:

• Age \<45 years.
• Complicated ataract.
• Coexisting ocular disorders (Glaucoma, Pseudoexfoliation Syndrome, Sublaxation, Chronic Iridocyclitis).
• Previous ocular surgery.
• Complicated phacoemulsification.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, Sohag Governorate, 82511, Egypt

RECRUITING

MeSH Terms

Interventions

Microscopy, Acoustic

Intervention Hierarchy (Ancestors)

Microscopy; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Ultrasonography; Investigative Techniques

Central Study Contacts

Mennatullah A Farrag, MBBCH

CONTACT

00201129595307; menaa.adel@med.sohag.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of Ophthalmology, Faculty of Medicine, Sohag University, Egypt

Study Record Dates

• First Submitted: August 12, 2026
• First Posted: August 18, 2026
• Study Start: October 1, 2025
• Primary Completion: October 1, 2026
• Study Completion: October 1, 2026
• Last Updated: August 18, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)