NCT07025707

Brief Summary

Agreement and Reproducibility of Intraocular Lens Tilt and Decentration Measurements: A Comparison between CASIA2 and CILT

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jul 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 28, 2025

Completed
20 days until next milestone

First Posted

Study publicly available on registry

June 17, 2025

Completed
14 days until next milestone

Study Start

First participant enrolled

July 1, 2025

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2025

Completed
Last Updated

June 17, 2025

Status Verified

June 1, 2025

Enrollment Period

1 month

First QC Date

May 28, 2025

Last Update Submit

June 15, 2025

Conditions

Intraocular Lens

Outcome Measures

Primary Outcomes (2)

  • Intraocular Lens Tilt (CASIA2 and CILT)

    Intraocular lens (IOL) tilt, measured in degrees, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Tilt is defined as the angle between the IOL plane and the corneal vertex.

    Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).

  • Intraocular Decentration (CASIA2 and CILT)

    Intraocular lens (IOL) decentration, measured in micrometers, assessed from anterior segment swept-source optical coherence tomography (AS-SS-OCT) images using the CASIA2 system and CILT software. Decentration is defined as the distance between the IOL center and the corneal vertex.

    Measured during the pre-surgery examination under normal pupil conditions and after pharmacologic dilation (45 minutes post-mydriatic instillation).

Eligibility Criteria

Age21 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

planned cataract surgery

You may qualify if:

  • planned cataract surgery
  • agreement to participation

You may not qualify if:

  • Zonulolysis
  • Strabismus
  • Reduced Compliance
  • Axial length \<20 or \>25 mm
  • Keratokonus
  • PEX

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Krankenhaus der Barmherzigen Brüder Wien

Vienna, Vienna, 1020, Austria

RECRUITING

Study Officials

  • Michael Amon, Prim. Univ. Prof. Dr.

    Hospital St. John of God

    STUDY CHAIR

Central Study Contacts

Konstantin Seiller-Tarbuk, Dr. med.

CONTACT

00431211215141konstantin.seiller@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 28, 2025

First Posted

June 17, 2025

Study Start

July 1, 2025

Primary Completion

August 1, 2025

Study Completion

September 1, 2025

Last Updated

June 17, 2025

Record last verified: 2025-06

Locations

AU(1)