Progression, Management, and Clinical Outcomes of Coronary Artery Aneurysms

NCT07764081 | Recruiting

• 1 other identifier: KY20250407-03
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to characterize the progression and risk fators of coronary artery aneurysms, and copmpare the outcomes across different management strategies

Conditions

Coronary Artery Disease; Aneurysms; Coronary Intervention

Keywords

Coronary Artery Aneurysms

Outcome Measures

Primary Outcomes (1)

• Progression of coronary artery aneurysm

  Progression of coronary artery aneurysm assessed by serial angiography or coronary computed tomography angiography

  6-12 months

Study Arms (1)

Coronary Artery Aneurysms

Patients with angiographically confirmed coronary artery aneurysms, defined as coronary dilation ≥1.5 times than the adjacent reference vessel diameter,

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients diagnosed with coronary artery aneurysm

You may qualify if:

• Angiographically confirmed coronary artery aneurysm, defined as coronary dilation ≥1.5 times the adjacent normal reference vessel diameter.
• Age 18-80 years.

You may not qualify if:

• Suboptimal image quality
• Incomplete clinical data, including medical history, laboratory parameters, or follow-up records.

Sponsors & Collaborators

• Nanjing First Hospital, Nanjing Medical University: lead

Study Sites (1)

Nanjing First Hospital

Nanjing, Jiangsu, 210006, China

RECRUITING

Related Publications (1)

• Nunez-Gil IJ, Cerrato E, Bollati M, Nombela-Franco L, Terol B, Alfonso-Rodriguez E, Camacho Freire SJ, Villablanca PA, Amat Santos IJ, de la Torre Hernandez JM, Pascual I, Liebetrau C, Camacho B, Pavani M, Albistur J, Latini RA, Varbella F, Jimenez-Diaz VA, Piraino D, Mancone M, Alfonso F, Linares JA, Rodriguez-Olivares R, Jimenez Mazuecos JM, Palazuelos Molinero J, Sanchez-Grande Flecha A, Gomez-Hospital JA, Ielasi A, Lozano I, Omede P, Bagur R, Ugo F, Medda M, Louka BF, Kala P, Escaned J, Bautista D, Feltes G, Salinas P, Alkhouli M, Macaya C, Fernandez-Ortiz A; CAAR investigators. Coronary artery aneurysms, insights from the international coronary artery aneurysm registry (CAAR). Int J Cardiol. 2020 Jan 15;299:49-55. doi: 10.1016/j.ijcard.2019.05.067. Epub 2019 Jul 19.

  PMID: 31378382 BACKGROUND

MeSH Terms

Conditions

Coronary Artery Disease; Aneurysm; Coronary Aneurysm

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Central Study Contacts

Fei Ye, MD

CONTACT

18951670287; doctor_ye@126.com

Yi-fei Wang, MD

CONTACT

18852577798; happywangyf2018@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: chief physician

Study Record Dates

• First Submitted: August 9, 2026
• First Posted: August 13, 2026
• Study Start: July 31, 2026
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): August 30, 2028
• Last Updated: August 13, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)