Reverse Fly Exercise On Supraspinatus Tendinitis In Patients Receiving Aromatase Inhibitors Therapy After Mastectomy

NCT07763080 | Recruiting DMC

• 2 other identifiers: P.T.REC/012/006575RD2607-208-234-212
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Reverse Fly Exercise On Supraspinatus Tendinitis In Patients Receiving Aromatase Inhibitors Therapy After Mastectomy

Conditions

Mastectomy; Aromatase Inhibitors Therapy

Keywords

Mastectomy; Aromatase inhibitors therapy

Outcome Measures

Primary Outcomes (2)

• Supraspinatus Tendon Thickness

  Using Dynamic ultrasonography for measuring

  Before 1st physical therapy session And after 8 weeks of regular 3 session per week of physical therapy

• Functional ability

  By Quik DASH Questionnaire

  Before 1st physical therapy session And after 8 weeks of regular 3 sessions/week of physical therapy

Study Arms (2)

Patients will receieve Reverse fly excercise

EXPERIMENTAL

This group will include 20 patients who will receive after 3:6 weeks from starting aromatase inhibitor the reverse fly exercise , in additions Traditional treatment for tendonitis post mastectomy and their medical treatment. (physiotherapeutic treatments 3 times a week for 8 weeks , including , (pendulum ex , soft tissue release , stretching ex., strengthening ex. and ROM ex.) and their medical treatment.

Other: Reverse fly excercise

Control group

OTHER

This group includes 20 patients who will receive the traditional physical therapy program (pendulum ex , soft tissue release, stretching ex., strengthening ex. and ROM ex.) and their medical treatment ,3 times a week for 8 weeks. 1.2 Criteria for the patient selection:

Other: Control group

Interventions

Reverse fly excercise OTHER

The procedure Stand with feet shoulder width apart while holding a dumbbell in each hand Flex the hips and knees slightly leaning the trunk forward while maintaining a neutral spine Allow the arms to hang perpendicular to the floor with elbows slightly flexed Horizontally abduct the shoulders by lifting the arms laterally until they are level with the shoulders Retract the scapulae at the top of the movement without elevating the shoulders Lower the arms slowly and with control back to the starting position Repeat for the desired number of repetitions

Patients will receieve Reverse fly excercise

Control group OTHER

This group includes 20 patients who will receive the traditional physical therapy program (pendulum ex , soft tissue release, stretching ex., strengthening ex. and ROM ex.) and their medical treatment ,3 times a week for 8 weeks. 1.2 Criteria for the patient selection:

Control group

Eligibility Criteria

• Age: 50 Years - 70 Years
• Gender Eligibility Details: Female Patient after mastectomy and receiving aromatase inhibitors therapy for 3:6 weeks before starting physical therapy
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age range between 50:70 years.
• Female patients participate in the study.
• All patients with unilateral mastectomy.
• Patients who receiving aromatase inhibitors treatment.
• All patients will enroll in this study with have their informed consent.

You may not qualify if:

• Patients have Metastases
• Patients with Lymphedema
• Patients with Rheumatoid arthritis
• Patients have Neurological deficits (stroke, Parkinsonism)
• Patients with Psychological disorders

Sponsors & Collaborators

• Cairo University: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

National Cancer Institute(NCI)

Cairo, Egypt

RECRUITING

Related Publications (3)

• Jatan N, Talo S, Azar AJ, Adrian TE, Kellett CF. Mechanisms and biomarkers for musculoskeletal signs and symptoms in patients treated with aromatase inhibitors: A comprehensive systematic review. Cancer Treat Rev. 2026 Feb;143:103075. doi: 10.1016/j.ctrv.2025.103075. Epub 2026 Jan 1.

  PMID: 41506128 BACKGROUND

• Kaidar-Person O, Poortmans P, Offersen BV, Siesling S, Sklair-Levy M, Meattini I, de Ruysscher D, Kuhn T, Boersma LJ. Spatial location of local recurrences after mastectomy: a systematic review. Breast Cancer Res Treat. 2020 Sep;183(2):263-273. doi: 10.1007/s10549-020-05774-4. Epub 2020 Jul 13.

  PMID: 32661665 BACKGROUND

• Lukasiewicz S, Czeczelewski M, Forma A, Baj J, Sitarz R, Stanislawek A. Breast Cancer-Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies-An Updated Review. Cancers (Basel). 2021 Aug 25;13(17):4287. doi: 10.3390/cancers13174287.

  PMID: 34503097 BACKGROUND

Related Links

• Related Info

MeSH Terms

Interventions

Control Groups

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Central Study Contacts

Nourhan Ahmed Mahmoud Souliman, Master degree

CONTACT

+201112852496; nourhan.souliman@pt.cu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asisstance lecturer of physical therapy

Model Details: RCT study

Study Record Dates

• First Submitted: August 5, 2026
• First Posted: August 13, 2026
• Study Start: August 18, 2026
• Primary Completion (Estimated): May 11, 2027
• Study Completion (Estimated): July 11, 2027
• Last Updated: August 19, 2026

Record last verified: 2026-08

Locations

EG (1)