Opportunistic Salpingectomy During Bariatric Surgery for Ovarian Cancer Prevention

NCT07761416 | Not Yet Recruiting Early Phase 1

• 1 other identifier: StJoseph
• Study Type: interventional
• Target: 66
• Locations: 0 countries
• Sites: N/A

Brief Summary

Ovarian cancer is a deadly disease that is hard to detect early and difficult to treat. Research shows that most ovarian cancers actually start in the fallopian tubes, not the ovaries. Removing the fallopian tubes (a procedure called salpingectomy) can lower the risk of ovarian cancer by about 80%. This procedure has no added risk to the patient, but does lead to sterilization and thus it is only offered to individuals who have completed child-bearing. Adding salpingectomy to another surgery that a patient is undergoing is called opportunistic salpingectomy and is already standard of practice in many gynecologic surgeries, such as hysterectomy. However, it is not yet commonly offered during weight-loss (bariatric) surgery, even though many patients having this surgery could benefit. This study will test whether it is practical and safe to offer fallopian tube removal during bariatric surgery at three hospitals in Canada. Patients who are eligible and interested will be invited to have their fallopian tubes removed at the same time as their planned weight-loss surgery. The research team will track whether the procedure can be completed successfully, whether there are any added complications, and how much extra time or resources are needed. The goal is to help make this cancer-prevention option available to more people.

Conditions

Ovarian Cancer; Bariatric Surgery; Opportunistic Salpingectomy

Outcome Measures

Primary Outcomes (1)

• Number of participants that successfully undergo opportunistic salpingectomy at time of their bariatric surgery

  From study commencement for 6 months

Secondary Outcomes (8)

• Length of hospital stay

  Length in days from admission to discharge from hospital, assessed up to 100 days

• 30-day hospital readmission rate

  From procedure end to 30 days postoperatively

• Blood transfusion

  From procedure start to 30 days postoperatively

• Surgical site infection

  From procedure end to 30 days postoperatively

• Additional OR time required

  From start of salpingectomy to end of salpingectomy, assessed up to 10 hours

Study Arms (1)

Opportunistic salpingectomy at bariatric surgery

EXPERIMENTAL

Addition of opportunistic salpingectomy to planned elective bariatric surgery

Procedure: Opportunistic salpingectomy at time of bariatric surgery

Interventions

Opportunistic salpingectomy at time of bariatric surgery PROCEDURE

Opportunistic salpingectomy (fallopian tube removal) at time of planned elective bariatric surgery

Opportunistic salpingectomy at bariatric surgery

Eligibility Criteria

• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals with fallopian tubes (no prior salpingectomy/salpingo-oophorectomy) who are undergoing an elective MBS and have completed child-bearing

You may not qualify if:

• unable to provide informed consent

Sponsors & Collaborators

• St. Joseph's Healthcare Hamilton: lead

MeSH Terms

Conditions

Ovarian Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Ovarian Diseases; Adnexal Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Neoplasms, Female; Urogenital Neoplasms; Genital Diseases; Endocrine System Diseases; Gonadal Disorders

Study Design

• Study Type: interventional
• Phase: early phase 1
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 3, 2026
• First Posted: August 12, 2026
• Study Start: August 1, 2026
• Primary Completion (Estimated): December 30, 2026
• Study Completion (Estimated): March 30, 2027
• Last Updated: August 12, 2026

Record last verified: 2026-08