NCT07759713

Brief Summary

Patient Information leaflet on varicoceles surgery

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
69

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2024

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2024

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2025

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

July 21, 2026

Completed
22 days until next milestone

First Posted

Study publicly available on registry

August 12, 2026

Completed
Last Updated

August 12, 2026

Status Verified

August 1, 2026

Enrollment Period

1.5 years

First QC Date

July 21, 2026

Last Update Submit

August 6, 2026

Conditions

Cryptozoospermia

Keywords

cryptozoospermiaVaricocelesvaricocelectomy

Outcome Measures

Primary Outcomes (1)

  • Semen

    Improvement in the semen concentration (measured by million/ml). This will be checked by repeat semen analysis 6 and 12 months in both study groups.

    12 months

Secondary Outcomes (1)

  • IVF/pregnancy outcomes

    12 months

Study Arms (2)

Medical Treatment

NO INTERVENTION

Medical treatment

Surgical

EXPERIMENTAL

Varicoceles surgery

Procedure: Varicoceles ligation

Interventions

Varicoceles ligationPROCEDURE

Microscopic surgery

Surgical

Eligibility Criteria

Age18 Years - 60 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsMale Infertility
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Male Infertility with cryptozoospermia and clinical varicoceles

You may not qualify if:

  • Genetic abnormalities. Other causes of male infertility

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Andrology department

Qina, Egypt

Location

MeSH Terms

Conditions

OligospermiaVaricocele

Condition Hierarchy (Ancestors)

Infertility, MaleGenital Diseases, MaleGenital DiseasesUrogenital DiseasesInfertilityMale Urogenital DiseasesVascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

July 21, 2026

First Posted

August 12, 2026

Study Start

February 1, 2024

Primary Completion

July 30, 2025

Study Completion

July 30, 2025

Last Updated

August 12, 2026

Record last verified: 2026-08

Locations

EG(1)