Ultrasound Scoring System for Diagnosis and Prediction of Severity and Surgical Outcomes of Placenta Accreta Spectrum

NCT07755709 | Not Yet Recruiting

• 1 other identifier: Soh-Med-26-7-7MS
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

Primary Objective: To determine the optimal cutoff values of the ultrasound score for different PAS subtypes (no PAS, placenta accreta, placenta increta, and placenta percreta). To evaluate the diagnostic accuracy of the novel Ultrasound Scoring System in predicting the severity of Placenta Accreta Spectrum (PAS) (placenta accreta, increta, and percreta). Secondary Objective:

• To correlate the novel ultrasound score with intraoperative findings (considered the gold standard) during cesarean delivery, including the degree of placental invasion and the need for surgical interventions (hysterectomy, bladder repair).
• To assess the relationship between the novel ultrasound score and postoperative complications, such as:
• Requirement for hysterectomy
• Bladder or bowel injury
• Blood transfusion requirement
• ICU admission rates
• To explore the potential for integrating the Ultrasound Scoring System with other clinical indicators (e.g., patient age, parity, and history of cesarean sections) to enhance the predictive accuracy for PAS.

Conditions

Placenta Accreta, Third Trimester

Keywords

placenta accreta

Outcome Measures

Primary Outcomes (1)

• degree of placental invasion and inability to conserve the uterus

  Need for Hysterectomy: Determined by the degree of placental invasion and inability to conserve the uterus \&Histopathogy confirmation. Bladder Injury: Recorded if any injury occurs during the procedure. Blood Transfusion Requirement: Amount of blood transfused intraoperatively. ICU Admission: Postoperative ICU admission requirement due to hemorrhage or other complications.

  1 week

Eligibility Criteria

• Age: 18 Years - 45 Years
• Gender Eligibility Details: Pregnant women aged 18 to 45 years. * Gestational age ≥28 weeks at the time of enrollment. * Diagnosed Placenta Previa with a history of: * One or more previous cesarean sections * Uterine scarring due to previous surgery as (myomectomy, D\&C, Metroplasty).
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Pregnant women aged 18 to 45 years. Gestational age ≥28 weeks at the time of enrollment. Diagnosed Placenta Previa with a history of: One or more previous cesarean sections Uterine scarring due to previous surgery as (myomectomy, D\&C, Metroplasty).

You may qualify if:

• Pregnant women aged 18 to 45 years.
• Gestational age ≥28 weeks at the time of enrollment.
• Diagnosed Placenta Previa with a history of:
• One or more previous cesarean sections
• Uterine scarring due to previous surgery as (myomectomy, D\&C, Metroplasty).
• Singleton pregnancy.

You may not qualify if:

• Women with multiple pregnancies (twins, triplets, etc.).
• Pregnancies complicated by acute medical conditions (e.g., heart failure, uncontrolled diabetes).
• Prior history of Blood diseases. (other than those related to pregnancy).
• Women who refuse to participate or withdraw consent during the study.

Sponsors & Collaborators

• Sohag University: lead

MeSH Terms

Conditions

Placenta Accreta

Condition Hierarchy (Ancestors)

Obstetric Labor Complications; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Placenta Diseases

Central Study Contacts

Ahmed Adel Khalifa, resident

CONTACT

01096679590; ahmedarsnl@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ahmed Adel Khalifa Mansour

Study Record Dates

• First Submitted: August 4, 2026
• First Posted: August 10, 2026
• Study Start: August 4, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): June 1, 2027
• Last Updated: August 10, 2026

Record last verified: 2026-08