NCT07236060

Brief Summary

By using 2d Ultrasound on 3rd trimester pregnant women, a model is made to help differentiate between placenta accreta spectrum and uterine scar dehiscence before operative action to help prepare multi-disciplinary steps if needed

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
7mo left

Started Nov 2025

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress44%
Nov 2025Dec 2026

First Submitted

Initial submission to the registry

September 30, 2025

Completed
2 months until next milestone

Study Start

First participant enrolled

November 15, 2025

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 19, 2025

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 15, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2026

Last Updated

November 19, 2025

Status Verified

September 1, 2025

Enrollment Period

1 year

First QC Date

September 30, 2025

Last Update Submit

November 14, 2025

Conditions

Placenta Accreta, Third TrimesterUterine Scar Dehiscence

Outcome Measures

Primary Outcomes (8)

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: Placental site

    (gestational age 28wk-full term) till operation

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: placental thickness

    (gestational age 28wk- full term) till operation

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: placental size

    (gestational age 28wk- fullterm) till operation

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: placental lacunae

    (gestational age 28wk-full term) till operation

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: Loss of placental hypoechoic zone

    (gestattional age 28wk-full term) till operation

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: Mean systolic velocity in both uterine arteries

    (gestational age 28wks-full term) till time of operation

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: Peak systolic velocity in uteroplacental interface

    (gestational age 28wks- full term) till operation

  • Model for percise diagnosis of placenta accreta spectrum Using 2d and/or 3d ultrasound doppler to assess: Peak systolic velocity in uterovesical interface

    (gestational age 28wks- full term) ill operation

Secondary Outcomes (8)

  • precise diagnosis of uterine dehiscence Using 2d and/or 3d ultrasound doppler to assess: Placental site

    (gestational age 28wk- fullterm) till operation

  • precise diagnosis of uterine dehiscence Using 2d and/or 3d ultrasound doppler to assess: Placental size

    (gestational age 28wk- full term)till the operation

  • precise diagnosis of uterine dehiscence Using 2d and/or 3d ultrasound doppler to assess: Placental thickness

    (gestational age 28wk-full term) till operation

  • precise diagnosis of uterine dehiscence Using 2d and/or 3d ultrasound doppler to assess: Placental lacunae

    (gestational age 28wk- fullterm) till operation

  • precise diagnosis of uterine dehiscence Using 2d and/or 3d ultrasound doppler to assess: Loss of placental hypoechoic zone

    (gestational age 28wks - fullterm) till operation

  • +3 more secondary outcomes

Interventions

2D ultrasound dopplerDEVICE

using 2d ultrasound doppler to form a model that will help distinguish between placenta accreta spectrum and uterine scar dehiscence pre-operatively

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Female patients admitted to women health hospital, Assiut university, Assiut

You may qualify if:

  • Women in 3rd trimester pregnancy with low lying placenta previa
  • History of 1 or more C-section
  • Patients planning to deliver baby in Assiut women health hospital
  • Willing and able to participate

You may not qualify if:

  • Antepartum Hemorrhage(sever attack) as it hinders time for accurate diagnosis and calling expert team of diagnosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Placenta Accreta

Condition Hierarchy (Ancestors)

Obstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesPlacenta Diseases

Central Study Contacts

Mostafa A Askalany

CONTACT

+201022554284mostafaaskalany90@yahoo.com

Hassan s Kamel

CONTACT

+201006664910kamelhs108@gmail.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident

Study Record Dates

First Submitted

September 30, 2025

First Posted

November 19, 2025

Study Start

November 15, 2025

Primary Completion (Estimated)

November 15, 2026

Study Completion (Estimated)

December 15, 2026

Last Updated

November 19, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share